Light-scattering instrument to detect thromboemboli in blood.

Light-scattering instrument to detect thromboemboli in blood.
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光散射仪检测血液中的血栓栓塞。

DOI:
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发表时间:
2003
影响因子:
3.5
通讯作者:
F. Mohammad
F. Mohammad
中科院分区:
医学3区
文献类型:
--
作者:
K. Solen;S. Sukavaneshvar;Yu Zheng;Brian Hanrahan;M. Hall;P. Goodman;B. Goodman;F. Mohammad

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通过详细介绍其最先进的配置,讨论仪器校准的理论和经验方面,并总结得益于该仪器的各种实验研究,描述了光散射微栓塞检测器(LSMD)的特性和能力。在过去,由于缺乏可以检测和量化循环血液中血栓栓塞的仪器,血液接触医疗设备通常会导致血栓栓塞,因此无法进行科学审查。最近,LSMD在全血中提供连续、无创检测血栓栓塞的能力(意味着LSMD探针不接触血液)被用于各种体外和离体模型,以探索血栓栓塞现象。通过这项工作,LSMD发展成为一种敏感和经济的研究工具,用于血栓栓塞现象的研究。
The characteristics and capabilities of a light-scattering microemboli detector (LSMD) are delineated by detailing its state-of-the-art configuration, by discussing the theoretical and empirical aspects of instrument calibration, and by summarizing various experimental studies that have benefited from this instrument. In the past, thromboembolism, which often results when blood contacts medical devices, has eluded scientific scrutiny due to the absence of instruments that could detect and quantify thromboemboli in circulating blood. More recently, the ability of the LSMD to provide continuous, noninvasive detection of thromboemboli in whole blood (meaning that the LSMD probe does not contact the blood) was exploited in various in vitro and ex vivo models to explore thromboembolic phenomena. Through this work, the LSMD evolved as a sensitive and an economical research tool for the study of thromboembolic phenomena.
猪模型体外循环期间中性粒细胞动态和肺、氧合器和动脉过滤器中的滞留。
DOI: 10.1097/00002480-199407000-00059
发表时间: 1994
期刊: ASAIO journal (American Society for Artificial Internal Organs : 1992)
影响因子: --
作者:
Dewanjee,MK;Palatianos,GN;Kapadvanjwala,M;Hsu,LC;Novak,S;Balantino,G;Serafini,AN;Dietrich,WD;Sfakianakis,GN
通讯作者: Sfakianakis,GN