Low-invasive Heating and Temperature Measurement Method for Hyperthermia Treatment using the Metal Coated Ferromagnetic Implant with Low Curie Temperature

Low-invasive Heating and Temperature Measurement Method for Hyperthermia Treatment using the Metal Coated Ferromagnetic Implant with Low Curie Temperature
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低居里温度金属涂层铁磁植入体热疗的低创加热及温度测量方法

DOI:
10.5220/0003152803410344
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发表时间:
2011
期刊:
--
影响因子:
--
通讯作者:
N. Yoshimura
N. Yoshimura
中科院分区:
--
文献类型:
--
作者:
K. Mitobe;N. Yoshimura

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热疗已被用于治疗各种类型的恶性肿瘤多年,因为肿瘤细胞比正常组织细胞对42-45°C范围内的温度更敏感。在本研究中,我们的目的是发展局部加热方法和监测方法,用于高温使用铁磁植入物与低居里温度(FILCT)在高频磁场下。FILCT的热生成效率低,导致了使用这种方法作为床边工具的障碍。在这项研究工作中,我们用金属材料涂覆FILCT,以提高发热效率。FILCT的磁导率在居里温度附近降低,因此可以通过非侵入性地测量人体外部磁通量的变化矢量,将FILCT用作热探头。本文介绍了实验装置和体外实验结果。
Hyperthermia has been used for many years to treat various types of malignant tumor because tumor cells are more sensitive to temperature in the range of 42-45°C than are normal tissue cells. In this study, we aim to develop the local heating method and monitoring method for hyperthermia using the Ferromagnetic Implant with Low Curie Temperature (FILCT) under high frequency magnetic field. The heat generation inefficiency of FILCT causes a barrier in order to use this method as a bedside tool. In this research work, we coated the FILCT with a metal material in order to improve the heat generation efficiency. The magnetic permeability of FILCT decreased around the Curie temperature; therefore we can use FILCT as a thermal probe by measuring of the changing vector of the magnetic flux at the outside of human body noninvasively. In this paper, we describe about the experimental setup and in vitro experimental results.
DOI: 10.1111/j.1349-7006.2008.00726.x
发表时间: 2008-04
期刊: Cancer Science
影响因子: 5.7
作者:
H. Saito;K. Mitobe;Aki Ito;Y. Sugawara;K. Maruyama;Y. Minamiya;S. Motoyama;N. Yoshimura;J. Ogawa
通讯作者: H. Saito;K. Mitobe;Aki Ito;Y. Sugawara;K. Maruyama;Y. Minamiya;S. Motoyama;N. Yoshimura;J. Ogawa
DOI: --
发表时间: 2008
期刊:
影响因子: --
作者:
小林利泰;関川;王力群;斎籐恵一;川澄正史;K. Mitobe and N. Yoshimura
通讯作者: K. Mitobe and N. Yoshimura
DOI: 10.1111/j.1349-7006.2008.01072.x
发表时间: 2009-03-01
期刊: CANCER SCIENCE
影响因子: 5.7
作者:
Ito, Aki;Saito, Hajime;Ogawa, Jun-ichi
通讯作者: Ogawa, Jun-ichi