Sudden cardiac arrest during the COVID-19 pandemic: A two-year prospective evaluation in a North American community.
Sudden cardiac arrest during the COVID-19 pandemic: A two-year prospective evaluation in a North American community.
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DOI：
10.1016/j.hrthm.2023.03.025
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发表时间：
2023-07
期刊：
影响因子：
5.5
通讯作者：
Reinier, Kyndaron
中科院分区：
文献类型：
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作者：
Chugh, Harpriya S.;Sargsyan, Arayik;Nakamura, Kotoka;Uy-Evanado, Audrey;Dizon, Bernadine;Norby, Faye L.;Young, Christopher;Hadduck, Katy;Jui, Jonathan;Shepherd, Daniel;Salvucci, Angelo;Chugh, Sumeet S.;Reinier, Kyndaron
在2019冠状病毒病（COVID-19）大流行期间，报告了更高的心脏骤停（SCA）发生率和更低的生存率。然而，尚未评估在不断演变的大流行期间对SCA的持续影响。本研究旨在评估COVID-19于疫情爆发两年期间对SCA的影响。在加州文图拉县（2020年人口843，843; 44.1%西班牙裔）的一项前瞻性研究中，我们比较了COVID-19大流行前2年与前4年的SCA发病率和结局。在确定的2222例院外SCA病例中，907例发生在大流行期间（2020年3月至2022年2月），1315例发生在大流行前（2016年3月至2020年2月）。总体年龄标准化SCA年发病率从大流行前的39/100，000（95% CI [37-41]）增加到大流行期间的54/100，000（95% CI 50-57; P <.001）。在西班牙裔中，发病率增加了77%，从38/100，000（95%CI 34-43）增加到68/100，000（95%CI 60-76; P <0.001）。在非西班牙裔中，发病率增加了26%，从39/100，000（95%CI 37-42; P <.001）增加到50/100，000（95%CI 46-54）。SCA发病率与COVID-19感染率密切相关。在大流行期间，SCA存活率显著降低（15%至10%; P <0.001），西班牙裔比非西班牙裔更不可能接受旁观者心肺复苏（45%对55%; P = 0.005）和出现可电击心律（15%对24%; P = 0.003）。总体SCA发生率始终较高，生存结局始终较低，在COVID感染高峰期间的影响被夸大。这项较长的评估发现，西班牙裔美国人的SCA发病率增加更高，复苏情况更差。急性SCA护理的潜在种族特异性障碍需要紧急评估和干预。
Early during the coronavirus disease 2019 (COVID-19) pandemic, higher sudden cardiac arrest (SCA) incidence and lower survival rates were reported. However, ongoing effects on SCA during the evolving pandemic have not been evaluated. The purpose of this study was to assess the impact of COVID-19 on SCA during 2 years of the pandemic. In a prospective study of Ventura County, California (2020 population 843,843; 44.1% Hispanic), we compared SCA incidence and outcomes during the first 2 years of the COVID-19 pandemic to the prior 4 years. Of 2222 out-of-hospital SCA cases identified, 907 occurred during the pandemic (March 2020 to February 2022) and 1315 occurred prepandemic (March 2016 to February 2020). Overall age-standardized annual SCA incidence increased from 39 per 100,000 (95% confidence [CI] 37–41) prepandemic to 54 per 100,000 (95% CI 50–57; P <.001) during the pandemic. Among Hispanics, incidence increased by 77%, from 38 per 100,000 (95% CI 34–43) to 68 per 100,000 (95% CI 60–76; P <.001). Among non-Hispanics, incidence increased by 26%, from 39 per 100,000 (95% CI 37–42; P <.001) to 50 per 100,000 (95% CI 46–54). SCA incidence rates closely tracked COVID-19 infection rates. During the pandemic, SCA survival was significantly reduced (15% to 10%; P <.001), and Hispanics were less likely than non-Hispanics to receive bystander cardiopulmonary resuscitation (45% vs 55%; P = .005) and to present with shockable rhythm (15% vs 24%; P = .003). Overall SCA rates remained consistently higher and survival outcomes consistently lower, with exaggerated effects during COVID infection peaks. This longer evaluation uncovered higher increases in SCA incidence among Hispanics, with worse resuscitation profiles. Potential ethnicity-specific barriers to acute SCA care warrant urgent evaluation and intervention.
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影响因子：
15.1
作者：
McVaney KE;Pepe PE;Maloney LM;Bronsky ES;Crowe RP;Augustine JJ;Gilliam SO;Asaeda GH;Eckstein M;Mattu A;Fumagalli R;Aufderheide TP;Osterholm MT;Writing group on behalf of the Metropolitan EMS Medical Directors Global Alliance
通讯作者：
Writing group on behalf of the Metropolitan EMS Medical Directors Global Alliance
影响因子：
24
作者：
Chan, Paul S.;Girotra, Saket;McNally, Bryan
通讯作者：
McNally, Bryan
影响因子：
37.8
作者：
Fishman GI;Chugh SS;Dimarco JP;Albert CM;Anderson ME;Bonow RO;Buxton AE;Chen PS;Estes M;Jouven X;Kwong R;Lathrop DA;Mascette AM;Nerbonne JM;O'Rourke B;Page RL;Roden DM;Rosenbaum DS;Sotoodehnia N;Trayanova NA;Zheng ZJ
通讯作者：
Zheng ZJ
DOI：
10.1016/j.lana.2022.100220
发表时间：
2022-06
期刊：
Lancet regional health. Americas
影响因子：
--
作者：
Bilal U;Jemmott JB;Schnake-Mahl A;Murphy K;Momplaisir F
通讯作者：
Momplaisir F
DOI：
10.15585/mmwr.mm6948a3externalicon
发表时间：
2020-12-04
影响因子：
33.9
作者：
Podewils, Laura Jean;Burket, Tori L.;Hasnain-Wynia, Romana
通讯作者：
Hasnain-Wynia, Romana