Exercise Interventions in Cardio-Oncology Populations
Exercise Interventions in Cardio-Oncology Populations
复制标题
心脏肿瘤人群的运动干预
DOI：
10.1097/jcn.0000000000000664
复制
发表时间：
2020
期刊：
影响因子：
--
通讯作者：
Harleah G. Buck
中科院分区：
文献类型：
--
作者：
Hsiao;L. Cousin;M. Fradley;Kristine A. Donovan;Barbara Smith;L. Szalacha;Ellen M. Lavoie Smith;Harleah G. Buck
补充数字内容可在文本中找到。癌症患者的心脏毒性是由化疗、靶向药物或胸部放疗对心血管系统的治疗相关损伤引起的。同时患有癌症和心血管疾病的肿瘤患者经常感到疲劳。在临床指南中建议运动，以管理癌症治疗期间或之后的疲劳。目的本文的目的是对心脏肿瘤患者的运动随机临床试验进行范围审查，重点关注运动干预对患者心血管和疲劳结果的组成部分和影响。方法范围界定审查方法框架被认为是适当的，并使用。搜索关键词包括“癌症”、“肿瘤学”、“心脏肿瘤学”、“心力衰竭”、“体力活动”和“运动”。检索涉及大型数据库（PubMed、MEDLINE、科克伦综述和CINAHL）的系统检索，以及使用滚雪球技术手动检索参考文献列表、关键期刊、网页和该领域专家。结果共纳入12个随机临床试验。研究特征，运动方案与建议的一致性，具体的运动训练组成部分，以及心血管和疲劳结果进行了映射。结论解决这些差距的建议包括关注具有心脏毒性风险的非乳腺癌患者，根据各种医疗和生理特征开发基于精确的处方，并将疲劳症状体验添加为结果变量。
Supplemental digital content is available in the text. Background Cardiac toxicity in patients with cancer results from treatment-related damage to the cardiovascular system by chemotherapy, targeted agents, or thoracic radiation. Cardio-oncology patients with co-occurring cancer and cardiovascular disease frequently experience fatigue. Exercise is recommended in clinical guidelines to manage fatigue during or after cancer treatment. Purpose The purpose of this article is to conduct a scoping review of the exercise randomized clinical trials in cardio-oncology patients, focusing on the components and effects of exercise interventions on patient cardiovascular and fatigue outcomes. Methods A scoping review methodological framework was deemed appropriate and used. Key words for search included “cancer,” “oncology,” “cardio-oncology,” “heart failure,” “physical activity,” and “exercise.” Search involved systematic searches of large databases (PubMed, MEDLINE, Cochrane Review, and CINAHL) and hand searches of reference lists, key journals, webpages, and experts in the field using snowballing techniques. Results There were 12 randomized clinical trials included in this review. Study characteristics, accordance of exercise protocols with recommendations, specific exercise training components, and cardiovascular and fatigue outcomes were mapped. Conclusions Recommendations for addressing the gaps included focusing on non–breast-cancer patients with cardiac toxicity risks, developing precision-based prescriptions based on various medical and physiological characteristics, and adding fatigue symptom experience as an outcome variable.
影响因子：
8.9
作者：
Herrmann J;Lerman A;Sandhu NP;Villarraga HR;Mulvagh SL;Kohli M
通讯作者：
Kohli M
用于管理头颈癌患者中度和重度疲劳的行为体力活动干预——美国国立卫生研究院 ORBIT 模型的预疗效研究
影响因子：
2.6
作者：
Wang, Hsiao-Lan;McMillan, Susan C.;Vijayakumar, Nisha;McDonald, Sally;Huang, Li-Ting;Gwede, Clement;Padhya, Tapan;Russell, Jeffery;Vondruska, Karen;Buck, Harleah G.
通讯作者：
Buck, Harleah G.
影响因子：
3.4
作者：
Blaes A;Prizment A;Koene RJ;Konety S
通讯作者：
Konety S