A Behavioral Physical Activity Intervention to Manage Moderate and Severe Fatigue Among Head and Neck Cancer Patients—Pre-efficacy Study in the National Institutes of Health ORBIT Model

A Behavioral Physical Activity Intervention to Manage Moderate and Severe Fatigue Among Head and Neck Cancer Patients—Pre-efficacy Study in the National Institutes of Health ORBIT Model
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用于管理头颈癌患者中度和重度疲劳的行为体力活动干预——美国国立卫生研究院 ORBIT 模型的预疗效研究

DOI:
10.1097/ncc.0000000000000568
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发表时间:
2019
期刊:
影响因子:
2.6
通讯作者:
Buck, Harleah G.
Buck, Harleah G.
中科院分区:
医学2区
文献类型:
--
作者:
Wang, Hsiao-Lan;McMillan, Susan C.;Vijayakumar, Nisha;McDonald, Sally;Huang, Li-Ting;Gwede, Clement;Padhya, Tapan;Russell, Jeffery;Vondruska, Karen;Buck, Harleah G.

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背景癌症相关疲劳 (CRF) 会降低头颈癌 (HNC) 的生存率,是最常见、最严重、最令人痛苦的症状,对 HNC 患者的日常生活活动 (ADL) 依赖产生负面影响。尽管人们一致认为体力活动可以减轻癌症患者的 CRF,但这些患者在癌症治疗后仍保持体力不活动。 目的 通过健身分级运动锻炼游戏 (PAfitME) 评估基于家庭的个性化行为体力活动干预的干预组成部分、干预实施模式和干预接触时间/持续时间,并初步评估可行性、可接受性、安全性和结果。 方法本研究 (N = 8) 是一项单组、前后设计,旨在在 HNC 治疗结束时评估为期 6 周的 PAfitME。健康结果包括 CRF、ADL 依赖性和健身表现。行为结果是运动游戏的依从性。结果积极的健康和行为结果支持 PAfitME 协议,包括干预组成部分、干预实施模式和干预接触时间/持续时间。 PAfitME 干预措施是可行且可接受的,且依从率良好。没有不良事件的报告。 PAfitME 干预的结果是 CRF、ADL 依赖性、心肺健康、平衡、肌肉力量和肩部前屈都有显着改善,效果大小为大到中等。 结论
BackgroundCancer-related fatigue (CRF) reduces head and neck cancer (HNC) survival rates and is the most common, severe, and distressing symptom negatively impacting activities of daily living (ADLs) dependence among HNC patients. These patients remain physically inactive after their cancer treatment, although there is consensus that physical activity mitigates CRF in cancer patients.ObjectiveA home-based personalized behavioral p hysical a ctivity intervention with fit ness graded m otion e xergames (PAfitME) was evaluated for its intervention components, intervention delivery mode, and intervention contact time/duration with initial assessment of the feasibility, acceptability, safety, and outcomes.MethodsThis study (N= 8) was a single-group, pre-post design to evaluate a 6-week PAfitME at the end of HNC treatment. Health outcomes were CRF, ADL dependence, and fitness performance. Behavioral outcomes were exergame adherence.ResultsPositive health and behavioral outcomes support the PAfitME protocol including intervention components, intervention delivery mode, and intervention contact times/duration. The PAfitME intervention is feasible and acceptable with promising adherence rates. No adverse events were reported. There was marked improvement in CRF, ADL dependence, cardiorespiratory fitness, balance, muscle strength, and shoulder forward flexion, with large to moderate effect sizes as a result of the PAfitME intervention.Conclusion
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DOI: --
发表时间: 2009
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