Characteristics, complications and outcomes among 1549 patients hospitalised with COVID-19 in a secondary hospital in Madrid, Spain: a retrospective case series study.
Characteristics, complications and outcomes among 1549 patients hospitalised with COVID-19 in a secondary hospital in Madrid, Spain: a retrospective case series study.
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DOI：
10.1136/bmjopen-2020-042398
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发表时间：
2020-11-10
期刊：
影响因子：
2.9
通讯作者：
COVID@HUIL Working Group
中科院分区：
文献类型：
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作者：
Jiménez E;Fontán-Vela M;Valencia J;Fernandez-Jimenez I;Álvaro-Alonso EA;Izquierdo-García E;Lazaro Cebas A;Gallego Ruiz-Elvira E;Troya J;Tebar-Martinez AJ;Garcia-Marina B;Peña-Lillo G;Abad-Motos A;Macaya L;Ryan P;Pérez-Butragueño M;COVID@HUIL Working Group;COVID@HUIL Working Group
描述二级医院因COVID-19入院患者的人口统计学、临床、放射学和实验室特征以及结局。在西班牙马德里的因凡塔莱昂诺大学医院（ILUH），确诊为SARS-CoV-2的连续住院患者的回顾性病例系列。所有患者于2020年3月1日至2020年5月28日期间在ILUH接受鼻咽拭子逆转录酶PCR检测呈阳性，并被诊断患有COVID-19。共纳入1549例COVID-19病例（中位年龄69岁（IQR 55.0-81.0），57.5%为男性）。78.2%的患者至少有一种潜在的合并症，最常见的是高血压（55.8%）。最常见的症状是发烧（75.3%）、咳嗽（65.7%）和呼吸困难（58.1%）。81例（5.8%）患者入住重症监护室（ICU）（中位年龄62岁（IQR 51-71）; 74.1%为男性;中位住院时间9天（IQR 5-19）），其中82.7%需要有创通气支持。1393例患者在研究期结束时有结局（病死率：21.2%（296/1393））。与病死率相关的独立因素（OR; 95% CI）为：年龄（1.07; 1.06 ~ 1.09）、男性（2.86; 1.85 ~ 4.50）、神经系统疾病（1.93; 1.19 ~ 3.13）、慢性肾脏疾病（2.83; 1.40 ~ 5.71）和肿瘤（4.29; 2.40 ~ 7.67）。因COVID-19而占用的医院病床百分比几乎翻了一番（702/361），ICU的患者人数翻了两番（32/8）。中位住院时间为9天（IQR 6-14）。这项研究提供了在欧洲二级医院住院的COVID-19患者的临床特征、并发症和结局。死亡结局与复杂程度较高的医院报告的结局相似。
To describe demographic, clinical, radiological and laboratory characteristics, as well as outcomes, of patients admitted for COVID-19 in a secondary hospital. Retrospective case series of sequentially hospitalised patients with confirmed SARS-CoV-2, at Infanta Leonor University Hospital (ILUH) in Madrid, Spain. All patients attended at ILUH testing positive to reverse transcriptase-PCR on nasopharyngeal swabs and diagnosed with COVID-19 between 1 March 2020 and 28 May 2020. A total of 1549 COVID-19 cases were included (median age 69 years (IQR 55.0–81.0), 57.5% men). 78.2% had at least one underlying comorbidity, the most frequent was hypertension (55.8%). Most frequent symptoms at presentation were fever (75.3%), cough (65.7%) and dyspnoea (58.1%). 81 (5.8%) patients were admitted to the intensive care unit (ICU) (median age 62 years (IQR 51–71); 74.1% men; median length of stay 9 days (IQR 5–19)) 82.7% of them needed invasive ventilation support. 1393 patients had an outcome at the end of the study period (case fatality ratio: 21.2% (296/1393)). The independent factors associated with fatality (OR; 95% CI): age (1.07; 1.06 to 1.09), male sex (2.86; 1.85 to 4.50), neurological disease (1.93; 1.19 to 3.13), chronic kidney disease (2.83; 1.40 to 5.71) and neoplasia (4.29; 2.40 to 7.67). The percentage of hospital beds occupied with COVID-19 almost doubled (702/361), with the number of patients in ICU quadrupling its capacity (32/8). Median length of stay was 9 days (IQR 6–14). This study provides clinical characteristics, complications and outcomes of patients with COVID-19 admitted to a European secondary hospital. Fatal outcomes were similar to those reported by hospitals with a higher level of complexity.
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DOI：
10.15585/mmwr.mm6915e3
发表时间：
2020-04-17
期刊：
MMWR. Morbidity and mortality weekly report
影响因子：
--
作者：
Garg S;Kim L;Whitaker M;O'Halloran A;Cummings C;Holstein R;Prill M;Chai SJ;Kirley PD;Alden NB;Kawasaki B;Yousey-Hindes K;Niccolai L;Anderson EJ;Openo KP;Weigel A;Monroe ML;Ryan P;Henderson J;Kim S;Como-Sabetti K;Lynfield R;Sosin D;Torres S;Muse A;Bennett NM;Billing L;Sutton M;West N;Schaffner W;Talbot HK;Aquino C;George A;Budd A;Brammer L;Langley G;Hall AJ;Fry A
通讯作者：
Fry A
影响因子：
28.3
作者：
Gorbalenya, Alexander E.;Baker, Susan C.;Ziebuhr, John
通讯作者：
Ziebuhr, John
DOI：
10.1001/jama.2020.6775
发表时间：
2020-01-01
期刊：
JAMA, Journal of the American Medical Association
影响因子：
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作者：
Richardson, Safiya;Hirsch, Jamie S.;,
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影响因子：
24.3
作者：
Liang, Wen-hua;Guan, Wei-jie;He, Jian-xing
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中国武汉市 138 例 2019 新型冠状病毒感染肺炎住院患者的临床特征。
影响因子：
120.7
作者：
Wang, Dawei;Hu, Bo;Peng, Zhiyong
通讯作者：
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