Safety and Effectiveness of COVID-19 Vaccines: Results from a Cross-Sectional Survey among Staff, Workers and Students at an Egyptian University.
Safety and Effectiveness of COVID-19 Vaccines: Results from a Cross-Sectional Survey among Staff, Workers and Students at an Egyptian University.
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DOI：
10.3390/vaccines10060846
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发表时间：
2022-05-26
期刊：
影响因子：
7.8
通讯作者：
Elmazar, Mohamed M.
中科院分区：
文献类型：
--
作者：
Hamza, Marwa S.;Tikamdas, Rajiv;El Baghdady, Noha S.;Sayed, Moustafa;Elbarazi, Amani S.;Badary, Osama A.;Elmazar, Mohamed M.
大规模接种疫苗是防止COVID-19疫情蔓延的最有效策略。然而，对疫苗安全性和有效性的担忧仍然是疫苗接受的巨大障碍。本研究的目的是探索不同的COVID-19疫苗结果，包括COVID-19疫苗接种后不良事件和/或COVID-19感染的发生。通过分发针对埃及英国大学工作人员和学生的在线调查进行了一项横断面研究。共有637名参与者完全完成了调查。其中，609人（95.6%）接种了COVID-19疫苗。在接种疫苗的所有参与者中，只有12.6%的人在接种疫苗后报告了COVID-19感染。其中，只有2.8%的人报告有严重的症状，而9.9%的人报告没有或有轻微的症状。第一次与第二次给药后报告的最常见副作用是头痛（36.3% vs. 14.6%），疲倦和疲劳（26.9% vs. 10.7）和发热（25.6% vs. 6.7%）。总之，本研究探索了不同的COVID-19疫苗结果，其中第一剂后副作用的总体发生率高于第二剂后。COVID-19疫苗的副作用与胃肠道疾病、性别和COVID-19疫苗的类型有关。与男性相比，接种疫苗后症状在女性中更常见，与其他类型相比，病毒载体疫苗更常见。不同类型的COVID-19疫苗的有效性得到了接种后COVID-19感染发病率较低的证实。
Mass vaccination is the most effective strategy against the spread of the COVID-19 pandemic. However, concerns about the vaccine’s safety and effectiveness remain a huge obstacle to vaccine acceptance. The aim of the present study was to explore different COVID-19 vaccine outcomes, including the development of adverse events and/or COVID-19 infection following COVID-19 vaccination. A cross-sectional study was conducted by distributing an online survey targeting staff and students at the British university in Egypt. A total of 637 participants fully completed the survey. Of these, 609 (95.6%) participants received the COVID-19 vaccine. Only 12.6% of the total vaccinated participants reported COVID-19 infection after vaccination. Of these, only 2.8% reported having severe symptoms while 9.9% reported having no or mild symptoms. The most common side effects reported after the first vs. second dose were headache (36.3% vs. 14.6%), tiredness and fatigue (26.9% vs. 10.7), and fever (25.6% vs. 6.7%). In conclusion, the present study explored different COVID-19 vaccine outcomes where the overall incidence of side effects is higher after the first dose than after the second dose. There is a relationship between COVID-19 vaccines’ side effects and gastrointestinal disorders, gender, and the type of COVID-19 vaccine. Post-vaccination symptoms were more frequently reported in women compared to men and more frequent with viral vector vaccines compared to other types. The effectiveness of different types of COVID-19 vaccines was confirmed by the lower incidence rate of post-vaccination COVID-19 infection.
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影响因子：
3.8
作者：
Pandey K;Thurman M;Johnson SD;Acharya A;Johnston M;Klug EA;Olwenyi OA;Rajaiah R;Byrareddy SN
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期刊：
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影响因子：
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作者：
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DOI：
10.1515/med-2022-0452
发表时间：
2022
期刊：
Open medicine (Warsaw, Poland)
影响因子：
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作者：
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通讯作者：
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