Context-dependent encoding in the human auditory brainstem relates to hearing speech in noise: implications for developmental dyslexia.
Context-dependent encoding in the human auditory brainstem relates to hearing speech in noise: implications for developmental dyslexia.
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DOI:
10.1016/j.neuron.2009.10.006
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发表时间:
2009-11-12
期刊:
影响因子:
16.2
通讯作者:
Kraus, Nina
中科院分区:
文献类型:
--
作者:
Chandrasekaran, Bharath;Hornickel, Jane;Skoe, Erika;Nicol, Trent;Kraus, Nina
We examined context-dependent encoding of speech in children with and without developmental dyslexia by measuring auditory brainstem responses to a speech syllable presented in a repetitive or variable context. Typically developing children showed enhanced brainstem representation of features related to voice pitch in the repetitive context, relative to the variable context. In contrast, children with developmental dyslexia exhibited impairment in their ability to modify representation in predictable contexts. From a functional perspective, we found that the extent of context-dependent encoding in the auditory brainstem positively correlated with behavioral indices of speech perception in noise. The ability to sharpen representation of repeating elements is crucial to speech perception in noise, since it allows superior ‘tagging’ of voice pitch, an important cue for segregating sound streams in background noise. The disruption of this mechanism contributes to a critical deficit in noise-exclusion, a hallmark symptom in developmental dyslexia.
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影响因子:
9.8
作者:
Nahum M;Nelken I;Ahissar M
通讯作者:
Ahissar M
影响因子:
2.4
作者:
KLATT, DH
通讯作者:
KLATT, DH
DOI:
10.1073/pnas.0901123106
发表时间:
2009-08-04
影响因子:
11.1
作者:
Hornickel, Jane;Skoe, Erika;Kraus, Nina
通讯作者:
Kraus, Nina
影响因子:
5.3
作者:
Luo, Feng;Wang, Qianzhou;Yan, Jun
通讯作者:
Yan, Jun
DOI:
10.1044/jshr.3201.112
发表时间:
1989-03-01
期刊:
JOURNAL OF SPEECH AND HEARING RESEARCH
影响因子:
--
作者:
ELLIOTT, LL;HAMMER, MA;SCHOLL, ME
通讯作者:
SCHOLL, ME