Free-breathing 3D cardiac MRI using iterative image-based respiratory motion correction.

Free-breathing 3D cardiac MRI using iterative image-based respiratory motion correction.
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DOI:
10.1002/mrm.24538
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发表时间:
2013-10
影响因子:
3.3
通讯作者:
Nezafat, Reza
Nezafat, Reza
中科院分区:
医学3区
文献类型:
--
作者:
Moghari, Mehdi H.;Roujol, Sebastien;Chan, Raymond H.;Hong, Susie N.;Bello, Natalie;Henningsson, Markus;Ngo, Long H.;Goddu, Beth;Goepfert, Lois;Kissinger, Kraig V.;Manning, Warren J.;Nezafat, Reza

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自由呼吸心脏MRI通常采用5 mm门窗的横隔膜导航仪(NAV)门控进行呼吸运动补偿。由于门控窗口较窄,扫描效率较低,导致扫描时间较长,特别是对于呼吸模式不规则的患者。本文提出了一种新的回溯性运动补偿算法,在不影响图像质量的情况下,将选通窗口增加到15 mm,从而减少了自由呼吸心脏MRI的扫描时间。提出的算法通过优化心脏的锐度来迭代校正呼吸诱导的心脏运动。为了评价这一技术,从11名健康受试者(7名女性,25±9岁)获得了两个1.3mm~3分辨率的冠状动脉MRI数据集:一个是12.0±2.0分钟获得的5 mm门窗的NAV数据集,另一个是7.1±1.0分钟获得的15 mm门窗的NAV数据集。利用该算法对15 mm选通窗口采集的图像进行了校正,并与5 mm和15 mm选通窗口采集的未校正图像进行了比较。校正后的图像与门窗为5 mm的图像相比,图像质量分数、清晰度和冠状动脉长度相当(p>0.05),而扫描时间减少了1.7倍。
Respiratory motion compensation using diaphragmatic navigator (NAV) gating with a 5 mm gating window is conventionally used for free-breathing cardiac MRI. Due to the narrow gating window, scan efficiency is low resulting in long scan times, especially for patients with irregular breathing patterns. In this work, a new retrospective motion compensation algorithm is presented to reduce the scan time for free-breathing cardiac MRI that increasing the gating window to 15 mm without compromising image quality. The proposed algorithm iteratively corrects for respiratory-induced cardiac motion by optimizing the sharpness of the heart. To evaluate this technique, two coronary MRI datasets with 1.3 mm3 resolution were acquired from 11 healthy subjects (7 females, 25±9 years); one using a NAV with a 5 mm gating window acquired in 12.0±2.0 minutes and one with a 15 mm gating window acquired in 7.1±1.0 minutes. The images acquired with a 15 mm gating window were corrected using the proposed algorithm and compared to the uncorrected images acquired with the 5 mm and 15 mm gating windows. The image quality score, sharpness, and length of the three major coronary arteries were equivalent between the corrected images and the images acquired with a 5 mm gating window (p-value>0.05), while the scan time was reduced by a factor of 1.7.
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