D2 antagonist during development decreases anxiety and infanticidal behavior in adult female prairie voles (Microtus ochrogaster).
D2 antagonist during development decreases anxiety and infanticidal behavior in adult female prairie voles (Microtus ochrogaster).
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DOI：
10.1016/j.bbr.2010.02.010
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发表时间：
2010-06-26
影响因子：
2.7
通讯作者：
Bales, Karen L.
中科院分区：
文献类型：
--
作者：
Hostetler, Caroline M.;Harkey, Shanna L.;Bales, Karen L.
On postnatal day eight, prairie vole pups were randomly assigned a treatment of 1 mg/kg SKF38393 (D1 agonist), quinpirole (D2 agonist), SCH23390 (D1 antagonist), eticlopride (D2 antagonist), or saline vehicle. As adults, females treated with eticlopride exhibited reduced anxiety-like behavior in an elevated plus maze and a reduction in infanticidal behavior. These behavioral effects were not seen in males. These data demonstrate that a single exposure to a D2 antagonist during development can have persistent, sex-specific effects on behavior into adulthood.
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影响因子：
3
作者：
CARTER, CS;GETZ, LL
通讯作者：
GETZ, LL
影响因子：
3.3
作者：
Bales, K. L.;Plotsky, P. M.;Carter, C. S.
通讯作者：
Carter, C. S.
影响因子：
1.9
作者：
Gingrich, B;Liu, Y;Insel, TR
通讯作者：
Insel, TR
影响因子：
5.5
作者：
Martelle JL;Nader MA
通讯作者：
Nader MA
影响因子：
2.9
作者：
INSEL, TR;PRESTON, S;WINSLOW, JT
通讯作者：
WINSLOW, JT