Two-way traffic on the bridge from innate to adaptive immunity.
Two-way traffic on the bridge from innate to adaptive immunity.
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桥上的双向交通从先天免疫到适应性免疫。
DOI：
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发表时间：
2010
影响因子：
6.5
通讯作者：
S. Ullrich
中科院分区：
文献类型：
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作者：
S. Ullrich
传统观点认为，信息通常从树突状细胞(DC)传递到T细胞。在这一期中，Schwarz和Schwarz证明了紫外线诱导的T调节细胞(Tregs)可以影响幼稚DC的生物学。他们报告说，当将分泌IL-10的Tregs注射到幼稚的小鼠体内时，DC可以激活额外的Tregs。有可能使用经过Tregs“教育”的DC在体内诱导免疫耐受。
Conventional wisdom suggests that information is usually transmitted from the dendritic cell (DC) to the T cell. In this issue, Schwarz and Schwarz demonstrate that UV-induced T regulatory cells (Tregs) can influence the biology of naïve DC. They report that IL-10-secreting Tregs prime DC to activate additional Tregs when injected into naïve mice. It may be possible to use DCs that have been "educated" by Tregs to induce immune tolerance in vivo.
影响因子：
56.9
作者：
M. Landi;J. Bauer;R. Pfeiffer;D. Elder;Ben Hulley;P. Minghetti;D. Calista;P. Kanetsky;D. Pinkel-D.-Pink
通讯作者：
M. Landi;J. Bauer;R. Pfeiffer;D. Elder;Ben Hulley;P. Minghetti;D. Calista;P. Kanetsky;D. Pinkel-D.-Pink
影响因子：
32.4
作者：
Shreedhar, V;Moodycliffe, AM;Flores-Romo, L
通讯作者：
Flores-Romo, L