Frequent recent origination of brain genes shaped the evolution of foraging behavior in Drosophila.
Frequent recent origination of brain genes shaped the evolution of foraging behavior in Drosophila.
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DOI:
10.1016/j.celrep.2011.12.010
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发表时间:
2012-02-23
期刊:
影响因子:
8.8
通讯作者:
Long M
中科院分区:
文献类型:
--
作者:
Chen S;Spletter M;Ni X;White KP;Luo L;Long M
The evolution of the brain and behavior are coupled puzzles. The genetic bases for brain evolution are widely debated, yet whether new genes impact the evolution of the brain and behavior is vaguely understood. Here we show that during recent evolution in Drosophila, new genes have frequently acquired neuronal expression, particularly in the mushroom bodies. Evolutionary signatures combined with expression profiling showed that natural selection influenced the evolution of young genes expressed in the brain, notably in mushroom bodies. Case analyses showed that two young retrogenes are expressed in the olfactory circuit and facilitate foraging behavior. Comparative behavioral analysis revealed divergence in foraging behavior between species. Our data suggest that during adaptive evolution new genes gain expression in specific brain structures and evolve new functions in neural circuits, which might contribute to the phenotypic evolution of animal behavior.
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