Sleep disordered breathing in hospitalized patients

Sleep disordered breathing in hospitalized patients
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住院患者睡眠呼吸障碍

DOI:
10.1007/s13665-016-0143-y
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发表时间:
2016
影响因子:
0.6
通讯作者:
V. Malik
V. Malik
中科院分区:
--
文献类型:
--
作者:
A. Mohan;A. Dhungana;V. Malik

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睡眠是一种普遍存在的现象,既有适应性又有恢复性。阻塞性睡眠呼吸暂停、肥胖-通气不足综合征、原发性中枢性睡眠呼吸暂停和潮式呼吸/复杂睡眠呼吸暂停是住院人群中最常见的睡眠相关呼吸障碍。睡眠呼吸障碍(SDB)在肥胖、充血性心力衰竭、慢性阻塞性肺病和骨关节炎的住院患者中更为常见。各种医院和ICU相关因素导致睡眠结构和昼夜节律的破坏。睡眠剥夺与更高的谵妄发生率、住院时间延长、住院期间死亡率和长期认知障碍有关。持续的睡眠剥夺也会导致免疫反应受损。现在有确凿的证据表明SDB与心血管疾病、中风、糖尿病、围手术期并发症和不良结局的患病率较高有关。因此,对于内科病房、重症监护病房和术后病房的患者,早期识别和治疗SDB变得非常重要。
Sleep is a ubiquitous phenomenon that is both adaptive and restorative. Obstructive sleep apnea, obesity–hypoventilation syndrome, primary central sleep apnea, and Cheyne–Stokes breathing/complex sleep apnea are the most common sleep-related breathing disorders encountered in the hospitalized population. Sleep disordered breathing (SDB) is commoner in hospitalized patients with obesity, congestive cardiac failure, COPD, and osteoarthritis. Various hospital and ICU-related factors contribute to disruption of sleep architecture and circadian rhythm. Sleep deprivation has been linked to higher incidence of delirium, prolonged hospitalization, and mortality during the hospital stay and long-term cognitive impairment. Persistent sleep deprivation also causes impairment in immune response. There is now a conclusive body of evidence linking SDB with higher prevalence of cardiovascular disease, stroke, diabetes, perioperative complications, and worse outcome. Hence, early recognition and treatment of SDB has become important for patients admitted in medical wards, critical care units, and post-surgical wards.
睡眠-觉醒周期和昼夜节律阶段的复杂相互作用调节健康受试者的情绪。
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