Neonatal Haemophilus influenzae infections.
Neonatal Haemophilus influenzae infections.
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新生儿流感嗜血杆菌感染。
DOI：
10.1136/adc.66.4_spec_no.437
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发表时间：
1991
影响因子：
5.2
通讯作者：
J. Eskola
中科院分区：
文献类型：
--
作者：
A. Takala;E. Pekkanen;J. Eskola
1985- 1989年期间，芬兰记录了9例新生儿流感嗜血杆菌败血症;发病率为2.8/100，000活产，占所有新生儿败血症病例的1.6%。所有病例的发病时间均较早，从分娩后0-6小时不等。7名婴儿早产，3名死亡（总死亡率33%）。在7例病例中从血液中分离出流感嗜血杆菌，在2例有败血症临床体征的新生儿中，在几个表面部位和胎盘上发现了流感嗜血杆菌。8株流感嗜血杆菌中有1株为荚膜型B和生物型I，其余为不可分型--分布与以前报道的相似。四个未封装的菌株是生物型III，和三个是生物型II。没有流感嗜血杆菌菌株是生物型IV，据报道这是新生儿和生殖器流感嗜血杆菌分离株的特征。所有9名母亲在分娩时或分娩后不久都有感染的迹象。从5名母亲中分离出流感嗜血杆菌：血液（n = 1）或胎盘或宫颈（n = 4）。宫内避孕器的使用可能是新生儿流感嗜血杆菌感染的一个可能的危险因素;其中两名母亲在怀孕期间放置了这种装置。
Nine cases of neonatal Haemophilus influenzae septicaemia were recorded in Finland during 1985-9; incidence was 2.8/100,000 live births, and 1.6% of all cases of neonatal septicaemia. The onset of the disease was early in all cases, ranging from 0-6 hours after delivery. Seven of the infants were preterm and three died (overall mortality 33%). H influenzae was isolated from blood in seven of the cases, and in two neonates with clinical signs of septicaemia it was found on several surface sites and the placenta. One of the eight strains of H influenzae was capsular type b and biotype I, the rest being non-typable--a distribution similar to those previously reported. Four of the uncapsulated strains were of biotype III, and three were of biotype II. None of the strains of H influenzae was of biotype IV, which has been reported to be characteristic of neonatal and genital isolates of H influenzae. All nine mothers had some sign of infection at the time of or shortly after delivery. H influenzae was isolated from five mothers: from the blood (n = 1) or from the placenta or cervix (n = 4). The use of intrauterine devices may be a possible risk factor for neonatal H influenzae infections; two of the mothers had such devices in place during their pregnancies.
b型流感嗜血杆菌分离株外膜蛋白亚型和生物型的比较。
DOI：
10.1093/infdis/144.5.480
发表时间：
1981
期刊：
The Journal of infectious diseases
影响因子：
--
作者：
Barenkamp,SJ;MunsonJr,RS;Granoff,DM
通讯作者：
Granoff,DM
在芬兰引起侵袭性感染的 B 型流感嗜血杆菌菌株的细菌流行病学。
DOI：
10.1093/infdis/160.2.237
发表时间：
1989
期刊：
The Journal of infectious diseases
影响因子：
--
作者：
Takala,AK;vanAlphen,L;Musser,JM;Geelen,L;Selander,RK;Eskola,J;Mäkelä,PH
通讯作者：
Mäkelä,PH