Substance use, mental illness, and familial conflict non-negotiation among HIV-positive African-Americans: latent class regression and a new syndemic framework.
Substance use, mental illness, and familial conflict non-negotiation among HIV-positive African-Americans: latent class regression and a new syndemic framework.
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DOI:
10.1007/s10865-015-9670-1
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发表时间:
2016-02
影响因子:
3.1
通讯作者:
Gallo, Joseph J.
中科院分区:
文献类型:
--
作者:
Robinson, Allysha C.;Knowlton, Amy R.;Gielen, Andrea C.;Gallo, Joseph J.
关键词:
We evaluated a synergistic epidemic (syndemic) of substance use, mental illness, and familial conflict non-negotiation among HIV-positive injection drug users (IDU). Baseline BEACON study data was utilized. Latent class analyses identified syndemic classes. These classes were regressed on sex, viral suppression, and acute care non-utilization. Females were hypothesized to have higher syndemic burden, and worse health outcomes than males. Nine percent of participants had high substance use/mental illness prevalence (Class 4); 23% had moderate levels of all factors (Class 3); 25% had high mental illness (Class 2); 43% had moderate substance use/mental illness (Class 1; N=331). Compared to Classes 1–3, Class 4 was mostly female (p<.05), less likely to achieve viral suppression, and more likely to utilize acute care (p<.05). Interventions should target African-American IDU females to improve their risk of negative medical outcomes. Findings support comprehensive syndemic approaches to HIV interventions, rather than singular treatment methods.
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