Comparison of the quick mild cognitive impairment (Qmci) screen and the SMMSE in screening for mild cognitive impairment.
Comparison of the quick mild cognitive impairment (Qmci) screen and the SMMSE in screening for mild cognitive impairment.
复制标题
快速轻度认知障碍（Qmci）筛查与 SMMSE 在筛查轻度认知障碍方面的比较。
DOI：
10.1093/ageing/afs059
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发表时间：
2012-09
期刊：
影响因子：
6.7
通讯作者：
Molloy DW
中科院分区：
文献类型：
--
作者：
O'Caoimh R;Gao Y;McGlade C;Healy L;Gallagher P;Timmons S;Molloy DW
轻度认知障碍（MCI）与正常认知障碍（NC）的鉴别是困难的。AB认知筛查（ABCS） 135在区分MCI和痴呆方面具有敏感性，对其进行了改进以提高敏感性和特异性，产生了快速轻度认知障碍（Qmci）筛查。目的：比较Qmci与标准化MMSE和ABCS 135的敏感性和特异性，以鉴别NC、MCI和痴呆。方法：改变ABCS 135的权重和子测试，并增加一个新的“逻辑内存”部分，创建Qmci。从加拿大安大略省的四家记忆诊所招募了335名受试者（154名轻度认知障碍患者，181名痴呆患者）并进行了全面评估。招募无认知症状的受试者的护理人员作为对照组（n = 630）。结果：Qmci鉴别轻度认知损伤与NC的曲线下面积（AUC）分别为0.86、0.67和0.83，高于SMMSE和ABCS 135；鉴别轻度认知损伤与轻度痴呆的曲线下面积（AUC）分别为0.92、0.91。对于75岁以上的患者，Qmci识别轻度认知障碍的能力更好。结论：Qmci比SMMSE对MCI和NC的鉴别更敏感，可作为临床诊断MCI，尤其是老年人MCI的有效检测手段。
Introduction: differentiating mild cognitive impairment (MCI) from normal cognition (NC) is difficult. The AB Cognitive Screen (ABCS) 135, sensitive in differentiating MCI from dementia, was modified to improve sensitivity and specificity, producing the quick mild cognitive impairment (Qmci) screen. Objective: this study compared the sensitivity and specificity of the Qmci with the Standardised MMSE and ABCS 135, to differentiate NC, MCI and dementia. Methods: weightings and subtests of the ABCS 135 were changed and a new section ‘logical memory’ added, creating the Qmci. From four memory clinics in Ontario, Canada, 335 subjects (154 with MCI, 181 with dementia) were recruited and underwent comprehensive assessment. Caregivers, attending with the subjects, without cognitive symptoms, were recruited as controls (n = 630). Results: the Qmci was more sensitive than the SMMSE and ABCS 135, in differentiating MCI from NC, with an area under the curve (AUC) of 0.86 compared with 0.67 and 0.83, respectively, and in differentiating MCI from mild dementia, AUC of 0.92 versus 0.91 and 0.91. The ability of the Qmci to identify MCI was better for those over 75 years. Conclusion: the Qmci is more sensitive than the SMMSE in differentiating MCI and NC, making it a useful test, for MCI in clinical practice, especially for older adults.
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影响因子：
158.5
作者：
Petersen, RC;Thomas, RG;Thal, LJ
通讯作者：
Thal, LJ
DOI：
10.1177/070674370505000110
发表时间：
2005-01-01
影响因子：
4
作者：
Molloy, DW;Standish, TIM;Lewis, DL
通讯作者：
Lewis, DL
影响因子：
9.9
作者：
Fisk, JD;Merry, HR;Rockwood, K
通讯作者：
Rockwood, K
影响因子：
7
作者：
Molloy, D W;Standish, T I
通讯作者：
Standish, T I
影响因子：
9.9
作者：
MCKHANN, G;DRACHMAN, D;STADLAN, EM
通讯作者：
STADLAN, EM