Epidemiological changes of respiratory syncytial virus (RSV) infections in Israel.
Epidemiological changes of respiratory syncytial virus (RSV) infections in Israel.
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DOI：
10.1371/journal.pone.0090515
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发表时间：
2014
期刊：
影响因子：
3.7
通讯作者：
Mandelboim M
中科院分区：
文献类型：
--
作者：
Hirsh S;Hindiyeh M;Kolet L;Regev L;Sherbany H;Yaary K;Mendelson E;Mandelboim M
呼吸道合胞病毒是婴儿下呼吸道感染的主要原因，因此需要深入的流行病学特征。我们在这里调查了2005-2012年间以色列呼吸道合胞病毒的类型分布。临床样本来自11,018名因呼吸道疾病住院的患者，并对各种呼吸道病毒的存在进行了评估，包括呼吸道合胞病毒A和合胞病毒B。直到2008年，每年的特点是存在一种主要类型的呼吸道合胞病毒。然而，从2008年开始，A型和B型呼吸道合胞病毒都在显著水平上被检测到，特别是在0-2岁的婴儿中。此外，自2008年以来，以色列境内流行的呼吸道合胞病毒A亚型和B亚型也发生了显著变化。最后，我们证明，与观察到的RSV流行病学变化无关，当2009年出现H1N1pdm09大流行病毒时，RSV感染被推迟，并在H1N1pdm09感染下降时被检测到。
RSV is the leading cause of lower respiratory-tract infections in infants and therefore demands in-depth epidemiological characterization. We investigated here the distribution of RSV types in Israel between the years 2005–2012. Clinical samples were collected from 11,018 patients hospitalized due to respiratory illnesses and were evaluated for the presence of various respiratory viruses, including RSV A and RSV B. Until 2008, each year was characterized by the presence of one dominant type of RSV. However, from 2008, both RSV A and B types were detected at significant levels, particularly among infants aged 0–2 years. Furthermore, significant changes in the RSV A and RSV B subtypes circulating in Israel since 2008 were observed. Finally, we demonstrate that, irrespectively of the changes observed in RSV epidemiology, when the pandemic H1N1pdm09 influenza virus appeared in 2009, RSV infections were delayed and were detected when infection with H1N1pdm09 had declined.
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影响因子：
4.8
作者：
Debiaggi M;Canducci F;Ceresola ER;Clementi M
通讯作者：
Clementi M
影响因子：
3.6
作者：
Hornsleth, A;Klug, B;Larsen, LB
通讯作者：
Larsen, LB
影响因子：
3.6
作者：
Jafri, Hasan S.;Wu, Xionghua;Henrickson, Kelly J.
通讯作者：
Henrickson, Kelly J.
DOI：
10.1056/nejmoa0804877
发表时间：
2009-02-05
期刊：
The New England journal of medicine
影响因子：
--
作者：
Hall CB;Weinberg GA;Iwane MK;Blumkin AK;Edwards KM;Staat MA;Auinger P;Griffin MR;Poehling KA;Erdman D;Grijalva CG;Zhu Y;Szilagyi P
通讯作者：
Szilagyi P
影响因子：
8
作者：
Levine, DA;Platt, SL;Kuppermann, N
通讯作者：
Kuppermann, N