Full-field displacement measurement of corneoscleral shells by combining multi-camera speckle interferometry with 3D shape reconstruction.
Full-field displacement measurement of corneoscleral shells by combining multi-camera speckle interferometry with 3D shape reconstruction.
复制标题
DOI：
10.1016/j.jmbbm.2019.103560
复制
发表时间：
2020-03
影响因子：
3.9
通讯作者：
Fazio MA
中科院分区：
文献类型：
--
作者：
Bianco G;Bruno L;Girkin CA;Fazio MA
眼结缔组织的生物力学性质的变化随着年龄的增长而发生，并且是几种眼部疾病如青光眼、近视和圆锥角膜的发展的基础。眼结缔组织的生物力学动力学通过离体膨胀测试来测量，其中眼内压（IOP）是变化的，并且使用光学方法来产生角膜和巩膜位移的图。目前的光学方法受到采集速率、遮挡、空间分辨率差和3D标测不足的限制。我们开发了一种干涉光学方法，该方法集成了四相机电子散斑干涉术（ESPI）和一种新的三维（3D）形状重建过程，以测量离体膨胀测试期间角膜和巩膜壳的形状和全场机械变形。每个摄像机提供了精确的测量激光束的相位相关的试样表面的变形;多视图立体视觉方法生成的试样的形状和功能形式，链接到试样的可见表面上的3D点的一个给定的摄像机的每个像素。以这种方式，试样的动态变形被局部化，与时间相关的纳米精度的试样的3D位移的量化。ESPI-3D系统适用于分析时变眼压引起的巩膜变形和形态变化。
Changes in the biomechanical properties of the connective tissue of the eye occur with age and underlie the development of several ocular diseases, such as glaucoma, myopia, and keratoconus. The biomechanical dynamics of ocular connective tissue are measured by ex vivo inflation testing, in which intraocular pressure (IOP) is varied and optical methods are used to produce maps of corneal and scleral displacement. Current optical methods are limited by acquisition rate, occlusions, poor spatial resolution, and insufficient 3D mapping. We developed an interferometric optical method integrates four-camera electronic speckle pattern interferometry (ESPI) and a novel three-dimensional (3D) shape reconstruction process to measure shape and full-field mechanical deformations of corneal and scleral shells during ex vivo inflation testing. Each camera provides accurate measurements of the laser beam phase related to deformations of the specimen surface; a multi-view stereovision method generates the shape of the specimen and a functional form that links every pixel of a given camera to 3D points on the specimen’s visible surface. In this way, dynamic deformations of the specimen are localized, with quantification of the time-dependent 3D displacements of the specimen at nanometric accuracy. The ESPI-3D system is suitable for analyzing scleral deformation and morphological changes caused by time-varying IOP.
登录
查看更多内容
影响因子：
4.6
作者：
Bruno, Luigi;Bianco, Gianfranco;Fazio, Massimo A.
通讯作者：
Fazio, Massimo A.
影响因子：
3.4
作者：
Elsheikh, Ahmed;Geraghty, Brendan;Rama, Paolo
通讯作者：
Rama, Paolo
DOI：
10.1115/1.4026224
发表时间：
2014-02-01
影响因子：
1.7
作者：
Pyne, Jeffrey D.;Genovese, Katia;Vande Geest, Jonathan P.
通讯作者：
Vande Geest, Jonathan P.
影响因子：
3.9
作者：
Rahman, I.;Maino, A.;Leatherbarrow, B.
通讯作者：
Leatherbarrow, B.
影响因子：
2
作者：
Elsheikh, Ahmed;Wang, Defu;Garway-Heath, David
通讯作者：
Garway-Heath, David