Four cases of Taenia saginata infection with an analysis of COX1 gene.

Four cases of Taenia saginata infection with an analysis of COX1 gene.
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DOI:
10.3347/kjp.2014.52.1.79
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发表时间:
2014-02
期刊:
The Korean journal of parasitology
影响因子:
--
通讯作者:
Chai JY
Chai JY
中科院分区:
其他
文献类型:
--
作者:
Cho J;Jung BK;Lim H;Kim MJ;Yooyen T;Lee D;Eom KS;Shin EH;Chai JY

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直到20世纪80年代,人类绦虫病在大韩民国(=韩国)并不罕见。流行率下降,2004年的一项全国调查显示没有带绦虫卵阳性病例。然而,随后在2012年进行的一项全国调查显示,带绦虫属的患病率为0.04%(10例)。鸡蛋暗示了它在韩国的复兴。我们最近遇到了4例牛带绦虫感染谁的症状,包括绦虫分泌节片。我们从每个病例中获得了几个节片。由于T.牛带绦虫与亚洲带绦虫几乎没有区别,采用PCR-RFLP和细胞色素c氧化酶亚基1(cox 1)的DNA测序进行分子分析,以确定种。4个样本的PCR-RFLP图谱均与T. cox 1基因序列与T. saginata的同源性为99.8-100%。saginata此前曾在韩国、日本、中国和柬埔寨报道过。4例患者均有出国旅行史,但与感染绦虫病的关系尚不明确。我们的研究结果可能提示T.在韩国的人群中感染了Saginata。
Human taeniases had been not uncommon in the Republic of Korea (=Korea) until the 1980s. The prevalence decreased and a national survey in 2004 revealed no Taenia egg positive cases. However, a subsequent national survey in 2012 showed 0.04% (10 cases) prevalence of Taenia spp. eggs suggesting its resurgence in Korea. We recently encountered 4 cases of Taenia saginata infection who had symptoms of taeniasis that included discharge of proglottids. We obtained several proglottids from each case. Because the morphological features of T. saginata are almost indistinguishable from those of Taenia asiatica, molecular analyses using the PCR-RFLP and DNA sequencing of the cytochrome c oxidase subunit 1 (cox1) were performed to identify the species. The PCR-RFLP patterns of all of the 4 specimens were consistent with T. saginata, and the cox1 gene sequence showed 99.8-100% identity with that of T. saginata reported previously from Korea, Japan, China, and Cambodia. All of the 4 patients had the history of travel abroad but its relation with contracting taeniasis was unclear. Our findings may suggest resurgence of T. saginata infection among people in Korea.
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