The aberrant, a morphological mutant of Hydra attenuata, has altered inhibition properties.
The aberrant, a morphological mutant of Hydra attenuata, has altered inhibition properties.
复制标题
该变异体是衰减水螅的形态突变体，其抑制特性发生了改变。
DOI：
10.1016/0012-1606(82)90321-9
复制
发表时间：
1982
影响因子：
2.7
通讯作者：
Bode,HR
中科院分区：
文献类型：
--
作者：
Rubin,DI;Bode,HR
移植实验导致了一种想法，即发育梯度涉及水螅的模式过程。头部激活和头部抑制梯度似乎与头部形成有关。如果这些梯度可以在动物体内改变，我们就可以了解更多关于图案形成的知识。达到这一目的的一种方法是研究被怀疑具有改变梯度的突变体。这种突变体可以通过其改变的形态来识别。在这项调查中，畸变，形态突变的水螅衰减，检查其梯度的变化。发现该异构体的抑制和极性性质发生了变化。抑制梯度大于正常，头部附近抑制水平高于正常。此外，从头部传递的抑制量大于正常，而通过胃区传递的抑制量小于正常。异常胃区极性的逆转比正常胃区困难，异常胃区极性的逆转比正常胃区快。这些变化的意义与模式的形成有关。
Transplantation experiments have led to the idea that developmental gradients are involved in the patterning processes of hydra. Head activation and head inhibition gradients appear to be involved in head formation. More could be learned about pattern formation if these gradients could be altered in the animal. One approach to this end is to study mutants suspected of having altered gradients. Such mutants may be identified by their altered morphology. In this investigation the aberrant, a morphological mutant ofHydra attenuata, was examined for alterations in its gradients. The aberrant was found to have changes in its inhibition and polarity properties. The inhibition gradient was steeper than normal and the level of inhibition was higher than normal near the head. In addition, the amount of inhibition transmitted from the head was greater than normal, while the amount of inhibition transmitted through the gastric region was less than normal. The polarity of the aberrant gastric region was more difficult than normal to reverse, and the aberrant extremities caused faster polarity reversal than normal extremities. The significance of these changes is discussed in relation to pattern formation.
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影响因子：
1.5
作者：
CAMPBELL, RD
通讯作者：
CAMPBELL, RD
影响因子：
56.9
作者：
H. Macwilliams;F. C. Kafatos
通讯作者：
F. C. Kafatos
影响因子：
2.7
作者：
R. Herlands;H. Bode
通讯作者：
H. Bode
Hydra 中的位置信息和位置信号
影响因子：
2.6
作者：
L. Wolpert;A. Hornbruch;M. Clarke
通讯作者：
M. Clarke
影响因子：
--
作者：
LOOMIS, WF;LENHOFF, HM
通讯作者：
LENHOFF, HM