Placental site trophoblastic tumour: a rare but potentially curable cancer
Placental site trophoblastic tumour: a rare but potentially curable cancer
复制标题
胎盘部位滋养细胞肿瘤：一种罕见但可能治愈的癌症
作者：
Am Gillespie;D. Liyim;J. Goepel;Re Coleman;Bw Hancock
胎盘部位滋养细胞肿瘤（PSTT）是一种罕见的妊娠滋养细胞疾病（GTD）。我们对1984年至1996年在谢菲尔德滋养层疾病筛查和治疗中心管理的所有PSTT病例进行了分析。在此期间，我们收到了4988例GTD注册，并管理了7例PSTT。观察到在怀孕前和发病之间有很大的间隔，最常见的症状是不规则阴道出血，伴有或不伴有先前的闭经。7例患者中有3例在诊断时疾病局限于子宫，并通过单独子宫切除术成功治疗。七名患者中有两名除了子宫肿瘤外还发生了肺转移，并接受了联合化疗——两人都活得很好。在剩下的两名患者中，一名远处转移，另一名局部转移，尽管进行了许多治疗干预，但两人都死亡。©2000癌症研究运动
Placental site trophoblastic tumour (PSTT) is a rare form of gestational trophoblastic disease (GTD). We have conducted an analysis of all cases of PSTT managed at the Trophoblastic Disease Screening and Treatment Centre, Sheffield, from 1984 to 1996. During this time we received 4988 registrations for GTD and managed seven cases of PSTT. A large range of interval between antecedent pregnancy and presentation was observed – the most common presenting symptoms being irregular vaginal bleeding with or without preceding amenorrhoea. Three out of seven patients had disease confined to the uterus at diagnosis and were successfully treated by hysterectomy alone. Two out of seven patients had pulmonary metastases in addition to uterine tumour and were treated with combination chemotherapy – both are alive and well. Of the remaining two patients one had distant and the other loco-regional metastases and both died despite numerous therapeutic interventions. © 2000 Cancer Research Campaign
胎盘催乳素和绒毛膜促性腺激素在正常胎盘和滋养层肿瘤中的免疫细胞化学定位，重点是中间滋养层和胎盘部位滋养层肿瘤。
DOI：
10.1097/00004347-198403010-00009
发表时间：
1984
期刊：
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
影响因子：
--
作者：
Kurman,RJ;Young,RH;Norris,HJ;Main,CS;Lawrence,WD;Scully,RE
通讯作者：
Scully,RE