Severity outcomes associated with SARS-CoV-2 XBB variants, an observational analysis.

Severity outcomes associated with SARS-CoV-2 XBB variants, an observational analysis.
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DOI:
10.1016/j.jcv.2023.105500
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发表时间:
2023-08
期刊:
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology
影响因子:
--
通讯作者:
Mostafa HH
Mostafa HH
中科院分区:
其他
文献类型:
--
作者:
Klein EY;Fall A;Norton JM;Eldesouki RE;Abdullah O;Han L;Yunker M;Mostafa HH

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SARS-CoV-2 XBB变体迅速占据主导地位的速度令人震惊。我们使用了2022年9月至2023年2月中旬诊断为Omicron感染的患者的大型队列,以评估感染XBB变体的患者入院或需要补充氧气的可能性。我们的数据显示XBB或XBB.1.5感染与入院之间没有显著关联。年龄较大的人群、缺乏疫苗接种、免疫抑制和潜在的心脏、肾脏和肺部疾病与住院有显著关联。
The rapidity with which SARS-CoV-2 XBB variants rose to predominance has been alarming. We used a large cohort of patients diagnosed with Omicron infections between September 2022 and mid-February 2023 to evaluate the likelihood of admission or need for supplemental oxygen in patients infected with XBB variants. Our data showed no significant association between XBB or XBB.1.5 infections and admissions. Older age groups, lack of vaccination, immunosuppression and underlying heart, kidney, and lung disease showed significant associations with hospitalization.
DOI: 10.1172/jci.insight.162007
发表时间: 2022-10-24
期刊: JCI INSIGHT
影响因子: 8
作者:
Morris, C. Paul;Eldesouki, Raghda E.;Fall, Amary;Gaston, David C.;Norton, Julie M.;Gallagher, Nicholas D.;Luo, Chun Huai;Abdullah, Omar;Klein, Eili Y.;Mostafa, Heba H.
通讯作者: Mostafa, Heba H.
DOI: 10.1093/bioinformatics/btab856
发表时间: 2022-03-04
期刊: Bioinformatics (Oxford, England)
影响因子: --
作者:
Chen C;Nadeau S;Yared M;Voinov P;Xie N;Roemer C;Stadler T
通讯作者: Stadler T