mHealth-Assisted Detection of Precursors to Relapse in Schizophrenia.
mHealth-Assisted Detection of Precursors to Relapse in Schizophrenia.
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DOI：
10.3389/fpsyt.2021.642200
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发表时间：
2021
影响因子：
4.7
通讯作者：
Ben-Zeev D
中科院分区：
文献类型：
--
作者：
Buck B;Hallgren KA;Campbell AT;Choudhury T;Kane JM;Ben-Zeev D
Theoretical views and a growing body of empirical evidence suggest that psychiatric relapses in schizophrenia-spectrum disorders (SSDs) have measurable warning signs. However, because they are time- and resource-intensive, existing assessment approaches are not well-suited to detect these warning signs in a timely, scalable fashion. Mobile technologies deploying frequent measurements—i.e., ecological momentary assessment—could be leveraged to detect increases in symptoms that may precede relapses. The present study examined EMA measurements with growth curve models in the 100 days preceding and following 27 relapses (among n = 20 individuals with SSDs) to identify (1) what symptoms changed in the periods gradually preceding, following, and right as relapses occur, (2) how large were these changes, and (3) on what time scale did they occur. Results demonstrated that, on average, participants reported elevations in negative mood (d = 0.34), anxiety (d =0.49), persecutory ideation (d =0.35), and hallucinations (d =0.34) on relapse days relative to their average during the study. These increases emerged gradually on average from significant and steady increases (d = 0.05 per week) in persecutory ideation and hallucinations over the 100-day period preceding relapse. This suggests that brief (i.e., 1–2 item) assessments of psychotic symptoms may detect meaningful signals that precede psychiatric relapses long before they occur. These assessments could increase opportunities for relapse prevention as remote measurement-based care management platforms develop.
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影响因子：
3.2
作者：
Chong HY;Teoh SL;Wu DB;Kotirum S;Chiou CF;Chaiyakunapruk N
通讯作者：
Chaiyakunapruk N
影响因子：
4.4
作者：
Palmier-Claus JE;Rogers A;Ainsworth J;Machin M;Barrowclough C;Laverty L;Barkus E;Kapur S;Wykes T;Lewis SW
通讯作者：
Lewis SW
精神分裂症患者的情绪低落：回顾性和实时措施的比较。
影响因子：
11.3
作者：
Blum, Lisa H.;Vakhrusheva, Julia;Saperstein, Alice;Khan, Samira;Chang, Rachel W.;Hansen, Marie C.;Zemon, Vance;Kimhy, David
通讯作者：
Kimhy, David
影响因子：
6.6
作者：
Granholm, Eric;Loh, Catherine;Swendsen, Joel
通讯作者：
Swendsen, Joel
影响因子：
10.5
作者：
Almond, S;Knapp, M;Brugha, T
通讯作者：
Brugha, T