Circulating leptin and pain perception among tobacco-dependent individuals.
Circulating leptin and pain perception among tobacco-dependent individuals.
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DOI：
10.1016/j.biopsycho.2015.02.008
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发表时间：
2015-04
影响因子：
2.6
通讯作者：
Allen, Sharon
中科院分区：
文献类型：
--
作者：
al'Absi, Mustafa;Lemieux, Andrine;Nakajima, Motohiro;Hatsukami, Dorothy K.;Allen, Sharon
Recent preclinical evidence suggests that leptin may modulate the stress response and may increase nociception. In this study, we examined for the first time the extent to which cigarette smoking is associated with leptin levels during an extended rest period and in response to noxious stimuli. Repeated blood samples were collected during a laboratory session from smokers and nonsmokers and assayed for leptin. Pain experiences, as well as neuroendocrine and cardiovascular measures, were collected across cold pressor and thermal heat pain tests. Both analysis of variance and correlations confirmed that smokers demonstrated dysregulations in leptin responsivity and association with pain relative to nonsmokers. The flat pattern of leptin release and the weak associations of this hormone with pain in smokers suggest a long-term effect of tobacco dependence on this regulatory hormone. In light of leptin’s influence on reward pathways, further investigation of leptin’s involvement in nicotine dependence is warranted.
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影响因子：
4.8
作者：
Heiman, ML;Ahima, RS;Flier, JS
通讯作者：
Flier, JS
DOI：
10.4021/jocmr1159w
发表时间：
2013-06
期刊：
Journal of clinical medicine research
影响因子：
--
作者：
Aguiar-Nemer AS;Toffolo MC;da Silva CJ;Laranjeira R;Silva-Fonseca VA
通讯作者：
Silva-Fonseca VA
DOI：
10.1073/pnas.0808023105
发表时间：
2008-12-09
影响因子：
11.1
作者：
Hollander, Jonathan A.;Lu, Qun;Kenny, Paul J.
通讯作者：
Kenny, Paul J.
影响因子：
2.3
作者：
Kalra, SP;Kalra, PS
通讯作者：
Kalra, PS
雌性双胞胎的唾液皮质醇和冷疼痛敏感性。
影响因子：
3.8
作者：
Godfrey, Kathryn M.;Strachan, Eric;Dansie, Elizabeth;Crofford, Leslie J.;Buchwald, Dedra;Goldberg, Jack;Poeschla, Brian;Succop, Annemarie;Noonan, Carolyn;Afari, Niloofar
通讯作者：
Afari, Niloofar