A Dynamic Interplay within the Frontoparietal Network Underlies Rhythmic Spatial Attention.

A Dynamic Interplay within the Frontoparietal Network Underlies Rhythmic Spatial Attention.
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额叶网络中的动态相互作用是有节奏的空间关注的基础。

DOI:
10.1016/j.neuron.2018.07.038
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发表时间:
2018-08-22
期刊:
影响因子:
16.2
通讯作者:
Kastner S
Kastner S
中科院分区:
医学1区
文献类型:
--
作者:
Fiebelkorn IC;Pinsk MA;Kastner S

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空间注意的经典研究假设其神经和行为效应随着时间的推移是连续的。最近的行为研究表明,空间注意力会导致感知灵敏度的提高或降低。然而,这些节律性波动的神经基础在很大程度上仍然是未知的。我们表明,猕猴额顶网络内的动态相互作用占空间注意力的节奏特性。神经振荡表征了额叶眼野(FEF)和外侧顶内区(LIP)之间的功能相互作用,θ相位(3-8 Hz)协调两个有节奏的交替状态。第一种是由FEF主导的β-波段活动定义的,与抑制的注意力转移有关,和LIP主导的γ-波段活动,与增强的视觉处理和更好的行为表现有关。第二种是由LIP特异性α-波段活动定义的,与减弱的视觉处理和更差的行为表现有关。我们的研究结果揭示了网络层面的相互作用如何将环境采样组织成有节奏的周期。Fiebelkorn等人,使用猕猴额顶叶网络的两个枢纽的同时录音,以证明在空间注意过程中有节奏的采样的神经基础。θ-组织的,交替的注意状态,其特征在于不同的时空动态,形状环境采样。
Classic studies of spatial attention assumed that its neural and behavioral effects were continuous over time. Recent behavioral studies have instead revealed that spatial attention leads to alternating periods of heightened or diminished perceptual sensitivity. Yet the neural basis of these rhythmic fluctuations has remained largely unknown. We show that a dynamic interplay within the macaque frontoparietal network accounts for the rhythmic properties of spatial attention. Neural oscillations characterize functional interactions between the frontal eye fields (FEF) and the lateral intraparietal area (LIP), with theta phase (3–8 Hz) coordinating two rhythmically alternating states. The first is defined by FEF-dominated beta-band activity, associated with suppressed attentional shifts, and LIP-dominated gamma-band activity, associated with enhanced visual processing and better behavioral performance. The second is defined by LIP-specific alpha-band activity, associated with attenuated visual processing and worse behavioral performance. Our findings reveal how network-level interactions organize environmental sampling into rhythmic cycles. Fiebelkorn et al., use simultaneous recordings in two hubs of the macaque frontoparietal network to demonstrate a neural basis of rhythmic sampling during spatial attention. Theta-organized, alternating attentional states, characterized by different spatiotemporal dynamics, shape environmental sampling.
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