Parent-Reported Suicidal Ideation in Three Population-Based Samples of School-Aged Korean Children With Autism Spectrum Disorder and Autism Spectrum Screening Questionnaire Screen Positivity.

Parent-Reported Suicidal Ideation in Three Population-Based Samples of School-Aged Korean Children With Autism Spectrum Disorder and Autism Spectrum Screening Questionnaire Screen Positivity.
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DOI:
10.1080/13811118.2020.1868367
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发表时间:
2022-07
影响因子:
2.8
通讯作者:
Kim, Young Shin
Kim, Young Shin
中科院分区:
医学4区
文献类型:
--
作者:
Bal, Vanessa H.;Leventhal, Bennett L.;Carter, Gregory;Kim, Hosanna;Koh, Yun-Joo;Ha, Mina;Kwon, Ho-Jang;Hong, Patricia;Kim, Young Shin

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据报道,自闭症患者的自杀率较高。本研究的目的是:1)估计自杀意念(SI)在流行病学确定的、以人群为基础的ASD儿童样本或孤独症谱筛查问卷(ASSQ)筛查阳性(ASP)中的患病率;2)确定ASD/ASP是否是SI的独立危险因素,控制已知的SI危险因素;以及3)建立ASD/ASP儿童SI的解释模型。参与者来自三个经流行病学证实的韩国学龄儿童样本(n=14,423;3,702;4,837)。AsSQ≥14是天冬氨酸天冬氨酸酶的分界点。1个亚样本(n=86)被确认为ASD。SI是基于家长对儿童行为评估系统-2-家长报告量表-儿童的项目的认可。Logistic回归用于评估SI和ASD/ASP之间的关联,控制人口统计学、同伴受害、行为问题和抑郁。为了建立ASD/ASP中SI的解释模型,测试了SI与儿童特征(共病条件、ASD症状、智商、适应功能)之间的关系。ASD和ASP儿童的SI(14%)和ASSQ筛查阴性(ASN)儿童的SI(16.6-27.4%)高于ASN儿童(3.4-6.9%)。与ASN相比,在控制了已知的SI危险因素后,ASD/ASP对SI有很强的预测性(OR:2.87-5.67)。在ASD和ASP组中,焦虑是SI的最强预测因子。在ASD和ASP儿童的非临床样本中,SI的患病率高于ASN同龄人。这些结果强调了对患有自闭症和社交困难的儿童,特别是那些高度焦虑的儿童进行SI常规筛查的必要性。
Higher prevalence of suicidality has been reported in individuals with ASD. This study aimed to: 1) Estimate the prevalence of suicidal ideation (SI) in epidemiologically-ascertained, population-based, samples of children with ASD or Autism Spectrum Screening Questionnaire (ASSQ) Screen Positivity (ASP); 2) Determine whether ASD/ASP is an independent risk factor for SI, controlling for known SI risk factors; and, 3) Develop an explanatory model for SI in children with ASD/ASP. Participants came from three epidemiologically-ascertained samples of school-aged Korean children (n=14,423; 3,702; 4,837). ASSQ≥14 was the cut-off for ASP. A subsample (n=86) was confirmed to have ASD. SI was based on parents’ endorsement of items on the Behavioral Assessment System for Children-2-Parent Report Scale-Children. Logistic regressions were used to assess associations between SI and ASD/ASP, controlling for demographics, peer victimization, behavior problems, and depression. To develop an explanatory model for SI within ASD/ASP, the associations between SI and child characteristics (comorbid conditions, ASD symptoms, IQ, adaptive function) were tested. SI was higher in children with ASD (14%) and ASP (16.6-27.4%) than ASSQ Screen Negative (ASN) peers (3.4-6.9%). ASD/ASP was strongly predictive of SI (ORs: 2.87-5.67), after controlling for known SI risk factors compared to ASN. Within the ASD and ASP groups, anxiety was the strongest predictor of SI. SI prevalence was higher in non-clinical samples of children with ASD and ASP, relative to ASN peers. These results underscore the need for routine screening for SI in children with ASD and social difficulties, particularly those with high anxiety.
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DOI: 10.1186/s13229-018-0226-4
发表时间: 2018
期刊: Molecular autism
影响因子: 6.2
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Cassidy S;Bradley L;Shaw R;Baron-Cohen S
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DOI: 10.1016/j.jaac.2018.01.023
发表时间: 2018-05-01
影响因子: 13.3
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