Evolutionary adaptations to dietary changes.

Evolutionary adaptations to dietary changes.
复制标题

DOI:
10.1146/annurev-nutr-080508-141048
复制
发表时间:
2010-08-21
影响因子:
8.9
通讯作者:
Di Rienzo A
Di Rienzo A
中科院分区:
医学2区
文献类型:
--
作者:
Luca F;Perry GH;Di Rienzo A

文献摘要

参考文献

被引文献

相似文献

通过文化创新以及栖息地和生态的变化,人类进化中出现了一些重大的饮食变化,包括吃肉,烹饪以及与植物和动物驯化有关的饮食。在现存灵长类动物(包括人类)的基因组中识别出适应这种饮食变化的特征,不仅可以揭示我们物种的进化历史,还可以揭示现代人类常见代谢疾病的机制。在这篇综述中,我们简要概述了古人类进化过程中发生的主要饮食变化,并讨论了用于识别序列变异模式中自然选择信号的方法和途径。然后,我们回顾了旨在检测在饮食适应中发挥重要作用的遗传位点的研究结果,并总结了未来在这一领域研究的潜力。
Through cultural innovation and changes in habitat and ecology, there have been a number of major dietary shifts in human evolution, including meat eating, cooking, and those associated with plant and animal domestication. The identification of signatures of adaptations to such dietary changes in the genome of extant primates (including humans) may shed light not only on the evolutionary history of our species, but also on the mechanisms that underlie common metabolic diseases in modern human populations. In this review, we provide a brief overview of the major dietary shifts that occurred during hominin evolution, and we discuss the methods and approaches used to identify signals of natural selection in patterns of sequence variation. We then review the results of studies aimed at detecting the genetic loci that played a major role in dietary adaptations and conclude by outlining the potential of future studies in this area.
DOI: 10.1016/s0092-8674(00)80705-9
发表时间: 2000-03-17
期刊: CELL
影响因子: 64.5
作者:
Adler, E;Hoon, MA;Zuker, CS
通讯作者: Zuker, CS
DOI: 10.1038/sj.ejcn.1601351
发表时间: 2002-03-01
影响因子: 4.7
作者:
Colagiuri, S;Miller, JB
通讯作者: Miller, JB
DOI: 10.1086/421051
发表时间: 2004-06-01
影响因子: 9.8
作者:
Bersaglieri, T;Sabeti, PC;Hirschhorn, JN
通讯作者: Hirschhorn, JN
DOI: 10.1038/nature04240
发表时间: 2005-10-20
期刊: NATURE
影响因子: 64.8
作者:
Bustamante, CD;Fledel-Alon, A;Clark, AG
通讯作者: Clark, AG
DOI: 10.1016/s0092-8674(00)80706-0
发表时间: 2000-03-17
期刊: CELL
影响因子: 64.5
作者:
Chandrashekar, J;Mueller, KL;Ryba, NJP
通讯作者: Ryba, NJP