Correlation between lactate dehydrogenase and other laboratory data in patients with atopic dermatitis
Correlation between lactate dehydrogenase and other laboratory data in patients with atopic dermatitis
复制标题
特应性皮炎患者乳酸脱氢酶与其他实验室数据的相关性
DOI：
10.1002/cia2.12225
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发表时间：
2022
影响因子：
1
通讯作者：
Sawamura Daisuke
中科院分区：
文献类型：
--
作者：
Kogawa Kazuhito;Minakawa Satoko;Matsuzaki Yasushi;Okamoto Asumi;Ogasawara Shu;Saito Norihiro;Sawamura Daisuke
Dear Editor, Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by pruritic and eczematous lesions. 1 AD is associated with elevated serum immunoglobulin (Ig) E levels, specific IgE environmental allergens such as house dust mites, and tissue and peripheral blood eosinophilia. 1 Since AD is thought to be a Th2-dominant inflammatory skin disease, especially in the acute phase, thymus and activation-regulated chemokine (TARC) is assumed to be involved in its pathogenesis. 2, 3Lactate dehydrogenase (LDH) is an enzyme present in most cells. Previous studies 4 found that elevated serum LDH5 levels are correlated with epidermal cell damage in eczema-associated erythroderma and changes in serum LDH levels can serve as a clinical marker for assessing the severity and clinical course of AD. 2 The aim of the present study was to explore the correlation between LDH levels and other laboratory data such as IgE and TARC levels and eosinophil count in patients with AD who visited Hirosaki University Hospital. This study was approved by the Committee of Medical Ethics of Hirosaki University Graduate School of Medicine in Aomori, Japan.
影响因子：
14.2
作者：
Leung, Donald Y. M.;Guttman-Yassky, Emma
通讯作者：
Guttman-Yassky, Emma