The Women and Infants Transmission Study (WITS) of Maternal-Infant HIV Transmission: Study Design, Methods, and Baseline Data
The Women and Infants Transmission Study (WITS) of Maternal-Infant HIV Transmission: Study Design, Methods, and Baseline Data
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母婴艾滋病毒传播的妇女和婴儿传播研究 (WITS)：研究设计、方法和基线数据
DOI：
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发表时间：
1996
期刊：
影响因子：
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通讯作者：
G. Alexander
中科院分区：
文献类型：
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作者：
A. Sheon;H. Fox;K. Rich;P. Stratton;Clemente Díaz;R. Tuomala;H. Mendez;J. Carrington;G. Alexander
摘要我们的目的是描述妇女和婴儿传播研究（WITS）的设计，数据收集方法和研究队列特征。WITS是在波士顿、芝加哥、曼哈顿、布鲁克林、圣胡安和休斯顿的妇产科和儿科诊所进行的一项关于孕妇及其婴儿HIV感染自然史的前瞻性流行病学研究。参与者是788名感染艾滋病毒的孕妇和她们所生的657名婴儿。主要的结果指标是与母婴传播和母亲和婴儿疾病进展相关的临床和实验室因素。在WITS中，82%的孕妇是有色人种。截至1993年6月30日登记的72%的孕妇和81%的婴儿在1994年3月继续接受随访。在出生后至少6个月随访并获得艾滋病毒培养结果的婴儿中，310名中有55名感染，传播率为17.7%。WITS招募了一名同伙..
ABSTRACT Our objective is to describe the Women and Infants Transmission Study (WITS) design, data collection methods, and study cohort characteristics. WITS is a prospective epidemiologic study of the natural history of HIV infection in pregnant women and their infants carried out at obstetric/gynecologic and pediatrie clinics in Boston, Chicago, Manhattan, Brooklyn, San Juan, and Houston. The participants were 788 HIV-infected pregnant women and 657 infants born to them. The main outcome measures were clinical and laboratory factors associated with maternal-infant transmission and disease progression in mothers and infants. Eighty-two percent of pregnant women in WITS are women of color. Seventy-two percent of the pregnant women and 81% of infants enrolled as of June 30,1993, remained in follow-up in March 1994. Among infants followed for at least 6 months from birth and on whom HIV culture results were available, 55 of 310 were infected, with a transmission rate of 17.7%. The WITS has recruited a cohor...
仪器、单克隆抗体和荧光染料对流式细胞术免疫表型分析的影响评估：基于 2 年 NIAID DAIDS 流式细胞术质量评估计划的报告。
DOI：
10.1006/clin.1993.1019
发表时间：
1993
期刊：
Clinical immunology and immunopathology
影响因子：
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作者：
Gelman,R;Cheng,SC;Kidd,P;Waxdal,M;Kagan,J
通讯作者：
Kagan,J
生命前 6 个月的血培养用于诊断垂直传播的人类免疫缺陷病毒感染。
DOI：
10.1093/infdis/170.4.996
发表时间：
1994
期刊：
The Journal of infectious diseases
影响因子：
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作者：
McIntosh,K;Pitt,J;Brambilla,D;Carroll,S;Diaz,C;Handelsman,E;Moye,J;Rich,K
通讯作者：
Rich,K
孕妇艾滋病毒感染误诊：对临床护理的影响。
DOI：
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发表时间：
1994
期刊：
Public health reports (Washington, D.C. : 1974)
影响因子：
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作者：
Sheon,AR;Fox,HE;Alexander,G;Buck,A;Higgins,A;McDermott,SM;Moroso,G;Moye,J;Pacheco-Acosta,E
通讯作者：
Pacheco-Acosta,E