Recurrent skin ulcer cross-repair and sensory reconstruction in a WRN gene mutational patient.
Recurrent skin ulcer cross-repair and sensory reconstruction in a WRN gene mutational patient.
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WRN基因突变患者复发性皮肤溃疡交叉修复与感觉重建
DOI：
10.1590/abd1806-4841.20187517
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发表时间：
2018-06
影响因子：
1.7
通讯作者：
Tang J
中科院分区：
文献类型：
--
作者：
He J;Pan D;Wu P;Tang J
一位37岁男性主诉左脚踝有一处难治性后踝溃疡。根据早老样的临床特征和基因检测，诊断为Werner综合征。为了接近溃疡，我们切取了一个带股前外侧皮神经的右股前外侧穿支皮瓣。一年后，他因右脚踝新的溃疡再次入院。我们切取带股前外侧皮神经的左股前外侧穿支皮瓣来修复缺损。经一年多的追踪，无溃疡复发，皮瓣的感觉在六个月后部分恢复。我们的结论是，自由流通股前外侧穿支皮瓣是一个可行的选择修复足部溃疡的沃纳综合征。
A 37-year-old man complained of a refractory posterior malleolar ulceration on his left ankle. He was diagnosed with Werner syndrome according to the progeroid clinical features and genetic testing. To approach the ulceration, a free flow-through right anterolateral thigh perforator flap with anterolateral thigh cutaneous nerve was harvested. One year later, he was readmitted due to a new ulceration on his right ankle. We harvested the left anterolateral thigh perforator flap with anterolateral thigh cutaneous nerve to reconstruct the defect. After one more year of follow-up, there was no recurrence of ulcers, and the sensation of the flap recovered partially after 6 months. We conclude that free flow-through anterolateral thigh perforator flap is a feasible choice for the repair of foot ulcers in Werner syndrome.
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影响因子：
13.1
作者：
Oshima, Junko;Sidorova, Julia M.;Monnat, Raymond J., Jr.
通讯作者：
Monnat, Raymond J., Jr.
影响因子：
2.1
作者：
Taniguchi, Y;Tamaki, T
通讯作者：
Tamaki, T
影响因子：
1.5
作者：
KOSHIMA, I;SHOZIMA, M;SOEDA, S
通讯作者：
SOEDA, S
影响因子：
1.5
作者：
Okazaki, M;Ueda, K;Kuriki, K
通讯作者：
Kuriki, K