Low back pain and lumbar spine osteoarthritis: how are they related?
Low back pain and lumbar spine osteoarthritis: how are they related?
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DOI：
10.1007/s11926-012-0305-z
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发表时间：
2013-02
影响因子：
5
通讯作者：
Jordan, Joanne M.
中科院分区：
文献类型：
--
作者：
Goode, Adam P.;Carey, Timothy S.;Jordan, Joanne M.
关键词：
腰椎骨关节炎（OA）非常常见，估计患病率为40- 85%。脊柱退行性变的过程通常被归类为OA（椎间隙狭窄伴椎体骨赘形成）;然而，在解剖学上，小关节是脊柱中唯一具有与关节突关节相似的病理退行性过程的滑膜关节。下背痛（LBP）也是一种常见的疾病，近80%的美国人一生中至少经历过一次LBP。脊柱X光片和LBP之间的复杂关系有许多临床和研究挑战。脊柱退变的具体保守治疗尚未建立;然而，最近人们对使用运动疗法感兴趣，因为在治疗慢性LBP方面有一些适度的益处。脊柱退行性变和腰痛之间的关系的理解可能会得到改善，在遗传学，生物标志物和疼痛通路领域的进一步人群为基础的研究。
Lumbar spine osteoarthritis (OA) is very common, with estimates of prevalence ranging from 40–85 %. The process of degeneration of the spine has commonly been classified as OA (disc space narrowing together with vertebral osteophyte formation); however, anatomically, the facet joint is the only synovial joint in the spine that has a similar pathological degenerative process to appendicular joints. Low back pain (LBP) is also a common condition, with nearly 80 % of Americans experiencing at least one episode of LBP in their lifetime. The complex relationship between spine radiographs and LBP has many clinical and research challenges. Specific conservative treatments for spine degeneration have not been established; there has, however, been recent interest in use of exercise therapy, because of some moderate benefits in treating chronic LBP. An understanding of the relationship between spine degeneration and LBP may be improved with further population-based research in the areas of genetics, biomarkers, and pain pathways.
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影响因子：
--
作者：
Hootman, JM;Helmick, CG
通讯作者：
Helmick, CG
DOI：
10.1002/art.24120
发表时间：
2008-10-15
期刊：
ARTHRITIS & RHEUMATISM-ARTHRITIS CARE & RESEARCH
影响因子：
--
作者：
Imamura, Marta;Imamura, Satiko Tomikawa;Camanho, Gilberto Luis
通讯作者：
Camanho, Gilberto Luis
影响因子：
3
作者：
HART, LG;DEYO, RA;CHERKIN, DC
通讯作者：
CHERKIN, DC
影响因子：
--
作者：
Giesecke, T;Gracely, RH;Clauw, DJ
通讯作者：
Clauw, DJ
影响因子：
--
作者：
Freburger, Janet K.;Holmes, George M.;Agans, Robert P.;Jackman, Anne M.;Darter, Jane D.;Wallace, Andrea S.;Castel, Liana D.;Kalsbeek, William D.;Carey, Timothy S.
通讯作者：
Carey, Timothy S.