COVID-19 and its Cardiac and Neurological Complications among Ontario Visible Minorities.

COVID-19 and its Cardiac and Neurological Complications among Ontario Visible Minorities.
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DOI:
10.1017/cjn.2021.148
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发表时间:
2022-07
期刊:
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques
影响因子:
--
通讯作者:
Moe GW
Moe GW
中科院分区:
其他
文献类型:
--
作者:
Chu JY;Kaliwal Y;Koh M;Chen R;Chow CM;Ko DT;Liu PP;Moe GW

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由于缺乏关于受冠状病毒病(COVID-19)影响的安大略有色人种(华人和南亚人)的流行病学、心脏和神经系统并发症的数据,因此进行了这项基于人群的回顾性研究,以系统地研究他们。从2020年1月1日至2020年9月30日,使用姓氏算法识别通过PCR检测呈COVID-19阳性的安大略华人和南亚人,与普通人群相比,分析了他们的人口统计学、心脏和神经系统并发症,包括住院和急诊率。发现中国(N = 1,186)COVID-19患者(平均年龄50.7岁)比一般人群(N = 42,547)(平均年龄47.6岁)更年长(p < 0.001),而南亚人(N = 3,459)更年轻(42.1岁)(p < 0.001)。中国人的30天心脏并发症粗发生率为169/10,000(p = 0.069),南亚人为64/10,000(p = 0.008),一般人群为112/10,000。对于神经系统并发症,中国人的30天粗发生率为160/10,000(p < 0.001);南亚人为40/10,000(p = 0.526),一般人群为48/10,000。中国人的30天全因死亡率显著高于一般人群(8.1% vs 5.0%,p < 0.001),而南亚人的30天全因死亡率较低,为2.1%(p < 0.001)。研究发现,在第一波疫情期间受COVID-19影响的安大略华人和南亚人在人口统计学、心脏和神经系统方面的结果存在显著差异。
Due to lack of data on the epidemiology, cardiac, and neurological complications among Ontario visible minorities (Chinese and South Asians) affected by coronavirus disease (COVID-19), this population-based retrospective study was undertaken to study them systematically. From January 1, 2020 to September 30, 2020 using the last name algorithm to identify Ontario Chinese and South Asians who were tested positive by PCR for COVID-19, their demographics, cardiac, and neurological complications including hospitalization and emergency visit rates were analyzed compared to the general population. Chinese (N = 1,186) with COVID-19 were found to be older (mean age 50.7 years) compared to the general population (N = 42,547) (mean age 47.6 years) (p < 0.001), while South Asians (N = 3,459) were younger (age of 42.1 years) (p < 0.001). The 30-day crude rate for cardiac complications among Chinese was 169/10,000 (p = 0.069), while for South Asians, it was 64/10,000 (p = 0.008) and, for the general population, it was 112/10,000. For neurological complications, the 30-day crude rate for Chinese was 160/10,000 (p < 0.001); South Asians was 40/10,000 (p = 0.526), and general population was 48/10,000. The 30-day all-cause mortality rate was significantly higher for Chinese at 8.1% vs 5.0% for the general population (p < 0.001), while it was lower in South Asians at 2.1% (p < 0.001). Chinese and South Asians in Ontario affected by COVID-19 during the first wave of the pandemic were found to have a significant difference in their demographics, cardiac, and neurological outcomes.
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