Psychosocial, Physical, and Neurophysiological Risk Factors for Chronic Neck Pain: A Prospective Inception Cohort Study.
Psychosocial, Physical, and Neurophysiological Risk Factors for Chronic Neck Pain: A Prospective Inception Cohort Study.
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DOI：
10.1016/j.jpain.2015.09.002
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发表时间：
2015-12
期刊：
影响因子：
4
通讯作者：
Maluf, Katrina S.
中科院分区：
文献类型：
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作者：
Shahidi, Bahar;Curran-Everett, Douglas;Maluf, Katrina S.
这项研究的目的是在从事高危职业的健康人群中确定首发慢性颈痛发生的可改变的危险因素。从以前的研究中确定的候选风险因素被分类为心理社会、生理和神经生理领域，在对171名上班族在受雇的前3个月内进行的基线评估中，同时对这些因素进行了评估。参与者在接下来的一年里完成了每月一次的在线调查，以确定是否存在慢性干扰性颈部疼痛，定义为颈部残疾指数在3个月或更长时间内得分≥5分。使用反向Logistic回归分析数据，以确定每个领域内的显著预测因素，然后将其输入根据年龄、性别和体重指数进行调整的多变量回归模型。基线时抑郁情绪(OR=3.36(1.10~10.31)，p=0.0 3)、颈伸耐力(OR=0.92(0.87~0.97，p=0.001)和弥漫性伤害性抑制控制(OR=0.90(0.83~0.98)，p=0.0 2)可预测慢性干扰性颈痛的发生。这些发现提供了第一个证据，表明先前存在情绪和下行疼痛调制障碍的人在暴露于外周伤害性刺激(如肌肉疲劳期间产生的刺激)时，患慢性颈痛的风险更大。
The purpose of this investigation was to identify modifiable risk factors for the development of first-onset chronic neck pain among an inception cohort of healthy individuals working in a high risk occupation. Candidate risk factors identified from previous studies were categorized into psychosocial, physical, and neurophysiological domains, which were assessed concurrently in a baseline evaluation of 171 office workers within the first 3 months of hire. Participants completed monthly online surveys over the subsequent year to identify the presence of chronic interfering neck pain, defined as a Neck Disability Index score ≥5 points for 3 or more months. Data were analyzed using backwards logistic regression to identify significant predictors within each domain, which were then entered into a multivariate regression model adjusted for age, sex, and body mass index. Development of chronic interfering neck pain was predicted by depressed mood (OR=3.36(1.10–10.31), p=0.03), cervical extensor endurance (OR=0.92(0.87–0.97), p=0.001), and diffuse noxious inhibitory control (OR=0.90(0.83–0.98), p=0.02) at baseline. These findings provide the first evidence that individuals with pre-existing impairments in mood and descending pain modulation may be at greater risk for developing chronic neck pain when exposed to peripheral nociceptive stimuli such as that produced during muscle fatigue.
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影响因子：
5
作者：
COHEN, S;KAMARCK, T;MERMELSTEIN, R
通讯作者：
MERMELSTEIN, R
影响因子：
2.3
作者：
Grimby-Ekman A;Andersson EM;Hagberg M
通讯作者：
Hagberg M
影响因子：
7.4
作者：
Côté, P;Cassidy, JD;Kristman, V
通讯作者：
Kristman, V
影响因子：
3.4
作者：
Beck, AT;Steer, RA;Ranieri, WF
通讯作者：
Ranieri, WF
DOI：
10.1038/nrrheum.2013.43
发表时间：
2013-06
期刊：
Nature reviews. Rheumatology
影响因子：
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作者：
通讯作者：
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