Respiratory amplitude guided 4-dimensional magnetic resonance imaging.
Respiratory amplitude guided 4-dimensional magnetic resonance imaging.
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DOI：
10.1016/j.ijrobp.2012.12.014
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发表时间：
2013-05-01
影响因子：
7
通讯作者：
Mutic, Sasa
中科院分区：
文献类型：
--
作者：
Hu, Yanle;Caruthers, Shelton D.;Low, Daniel A.;Parikh, Parag J.;Mutic, Sasa
旨在评价前瞻性引导四维（4D）磁共振成像（MRI）图像采集的可行性，使用预先选择的呼吸振幅触发以实现腹部运动跟踪的T2加权。开发了基于呼吸幅度的触发系统，并将其集成到商用快速自旋回波（TSE）MRI序列中。在健康人类受试者中进行了初步可行性测试。四种呼吸状态，吸气和呼气的中间和结束，用于触发肝脏的4DMRI图像采集。为了实现T2加权，回波时间（TE）和重复时间（TR）分别设置为75 ms和4108 ms。采用单次激发采集、并行成像和部分k空间成像技术提高图像采集效率。获取由轴向或矢状切片组成的4D MRI图像集。MRI扫描仪测量和记录的呼吸数据显示，触发事件发生在适当的呼吸水平。通过感测肝脏大小和形状（轴向）或横膈膜运动（矢状）的变化，可以在两个4DMRI图像数据集上容易地观察到肝脏运动。两个4DMRI图像数据集均按预期进行T2加权。这项工作证明了使用基于振幅的呼吸触发实现T2加权4DMRI图像的可行性。借助于基于呼吸幅度的触发系统，所提出的方法与大多数MRI序列兼容，因此具有改善腹部肿瘤运动成像中的肿瘤组织对比度的潜力。
To evaluate the feasibility of prospectively guiding 4-dimensional (4D) magnetic resonance imaging (MRI) image acquisition using triggers at pre-selected respiratory amplitudes to achieve T2 weighting for abdominal motion tracking. A respiratory amplitude based triggering system was developed and integrated into a commercial turbo spin echo (TSE) MRI sequence. Initial feasibility tests were performed on healthy human subjects. Four respiratory states, the middle and the end of inhalation and exhalation, were used to trigger 4DMRI image acquisition of the liver. To achieve T2 weighting, the echo time (TE) and repetition time (TR) were set to 75ms and 4108ms, respectively. Single-shot acquisition, together with parallel imaging and partial k-space imaging techniques, was used to improve image acquisition efficiency. 4D MRI image-sets composed of axial or sagittal slices were acquired. Respiratory data measured and logged by the MRI scanner showed that the triggers occurred at the appropriate respiratory levels. Liver motion could be easily observed on both 4DMRI image data-sets by sensing either the change of liver in size and shape (axial) or diaphragm motion (sagittal). Both 4DMRI image data-sets were T2 weighted as expected. This work demonstrated the feasibility of achieving T2 weighted 4DMRI images using amplitude based respiratory triggers. With the aid of the respiratory amplitude based triggering system, the proposed method is compatible with most MRI sequences and therefore has the potential to improve tumor-tissue contrast in abdominal tumor motion imaging.
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影响因子：
6.7
作者：
Plathow, C;Klopp, M;Kauczor, HU
通讯作者：
Kauczor, HU
影响因子：
3.3
作者：
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影响因子：
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作者：
Plathow, C;Ley, S;Kauczor, HU
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Kauczor, HU
DOI：
10.1016/s0360-3016(99)00056-5
发表时间：
1999-07-01
影响因子：
7
作者：
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通讯作者：
Martinez, AA
影响因子：
3.8
作者：
Low, DA;Nystrom, M;Whiting, BR
通讯作者：
Whiting, BR