A Novel Quantitative Parameter for Static Myocardial Computed Tomography: Myocardial Perfusion Ratio to the Aorta.
A Novel Quantitative Parameter for Static Myocardial Computed Tomography: Myocardial Perfusion Ratio to the Aorta.
复制标题
静态心肌计算机断层扫描：心肌灌注比与主动脉的新型定量参数。
DOI：
10.3390/jcm11071816
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发表时间：
2022-03-25
影响因子：
3.9
通讯作者：
Kido T
中科院分区：
文献类型：
--
作者：
Kouchi T;Tanabe Y;Takemoto T;Yoshida K;Yamamoto Y;Miyazaki S;Fukuyama N;Nishiyama H;Inaba S;Kawaguchi N;Kido T;Yamaguchi O;Kido T
我们评估了静态计算机断层扫描灌注（CTP）中心肌灌注与主动脉灌注比（MPR）检测单光子发射计算机断层扫描（SPECT）评估的心肌灌注异常的可行性。回顾性评价了25例可疑冠心病患者的动态CTP和SPECT。从动态CTP图像中选择在用于检测心肌灌注异常的次优相位扫描的CTP图像，并将其用作本研究中的静态CTP图像。将静态CTP的MPR诊断准确性与目视评估和常规定量参数（如心肌CT衰减（HU）和透壁灌注比（TPR））的诊断准确性进行比较。MPR的曲线下面积（0.84; 95% CI，0.76-0.90）显著高于心肌CT衰减（0.73; 95% CI，0.65-0.79）和TPR（0.76; 95% CI，0.67-0.83）（p < 0.05）。敏感性和特异性为67%（95% CI，54-77%）和90%（95% CI，86-92%）目视评估，51%（95% CI，39-63%）和86%（95% CI，82-89%）心肌CT衰减，63% TPR和MPR分别为78%（95%CI，66-86%）和84%（95%CI，80- 88%）。MPR对心肌灌注异常的诊断准确率高于心肌CT和TPR。
We evaluated the feasibility of myocardial perfusion ratio to the aorta (MPR) in static computed tomography perfusion (CTP) for detecting myocardial perfusion abnormalities assessed by single-photon emission computed tomography (SPECT). Twenty-five patients with suspected coronary artery disease who underwent dynamic CTP and SPECT were retrospectively evaluated. CTP images scanned at a sub-optimal phase for detecting myocardial perfusion abnormalities were selected from dynamic CTP images and used as static CTP images in the present study. The diagnostic accuracy of MPR derived from static CTP was compared to those of visual assessment and conventional quantitative parameters such as myocardial CT attenuation (HU) and transmural perfusion ratio (TPR). The area under the curve of MPR (0.84; 95% confidence interval [CI], 0.76–0.90) was significantly higher than those of myocardial CT attenuation (0.73; 95% CI, 0.65–0.79) and TPR (0.76; 95% CI, 0.67–0.83) (p < 0.05). Sensitivity and specificity were 67% (95% CI, 54–77%) and 90% (95% CI, 86–92%) for visual assessment, 51% (95% CI, 39–63%) and 86% (95% CI, 82–89%) for myocardial CT attenuation, 63% (95% CI, 51–74%) and 84% (95% CI, 80–88%) for TPR, and 78% (95% CI, 66–86%) and 84% (95% CI, 80–88%) for MPR, respectively. MPR showed higher diagnostic accuracy for detecting myocardial perfusion abnormality compared with myocardial CT attenuation and TPR.
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使用256片计算机断层扫描术的定性和定量评估三磷酸腺苷应力全心肌灌注成像。
影响因子：
3.7
作者：
Kurata A;Kawaguchi N;Kido T;Inoue K;Suzuki J;Ogimoto A;Funada J;Higaki J;Miyagawa M;Vembar M;Mochizuki T
通讯作者：
Mochizuki T
影响因子：
7.5
作者：
Takx, Richard A. P.;Blomberg, Bjorn A.;Leiner, Tim
通讯作者：
Leiner, Tim
影响因子：
37.8
作者：
Cerqueira, MD;Weissman, NJ;Verani, MS
通讯作者：
Verani, MS
影响因子：
2.6
作者：
Shrimpton, P. C.;Hillier, M. C.;Dunn, M.
通讯作者：
Dunn, M.
影响因子：
24
作者：
Jaarsma, Caroline;Leiner, Tim;Schalla, Simon
通讯作者：
Schalla, Simon