Bioimaging and subclinical cardiovascular disease in low- and middle-income countries.
Bioimaging and subclinical cardiovascular disease in low- and middle-income countries.
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DOI:
10.1007/s12265-014-9588-y
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发表时间:
2014-11
影响因子:
3.4
通讯作者:
Fuster, Valentin
中科院分区:
文献类型:
--
作者:
Vedanthan, Rajesh;Choi, Brian G.;Baber, Usman;Narula, Jagat;Fuster, Valentin
Cardiovascular disease (CVD) is the leading cause of mortality worldwide and also exerts a significant economic burden, especially in low- and middle-income countries (LMICs). Detection of subclinical CVD, before an individual experiences a major event, may therefore offer the potential to prevent or delay morbidity and mortality, if combined with an appropriate care response. In this review, we discuss imaging technologies that can be used to detect subclinical atherosclerotic CVD (carotid ultrasound, coronary artery calcification) and non-atherosclerotic CVD (echocardiography). We review these imaging modalities, including aspects such as rationale, relevance, feasibility, utilization, and access in LMICs. The potential gains in detecting subclinical CVD may be substantial in LMICs, if earlier detection leads to earlier engagement with the health care system to prevent or delay cardiac events, morbidity, and premature mortality. Thus, dedicated studies examining the feasibility, utility, and cost-effectiveness of detecting subclinical CVD in LMICs are warranted.
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DOI:
10.1016/j.jacr.2012.01.005
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期刊:
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