Bioimaging and subclinical cardiovascular disease in low- and middle-income countries.

Bioimaging and subclinical cardiovascular disease in low- and middle-income countries.
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DOI:
10.1007/s12265-014-9588-y
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发表时间:
2014-11
影响因子:
3.4
通讯作者:
Fuster, Valentin
Fuster, Valentin
中科院分区:
医学3区
文献类型:
--
作者:
Vedanthan, Rajesh;Choi, Brian G.;Baber, Usman;Narula, Jagat;Fuster, Valentin

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心血管疾病是世界范围内死亡的主要原因,也造成了巨大的经济负担,特别是在低收入和中等收入国家。因此,在个人经历重大事件之前发现亚临床心血管疾病,如果与适当的护理反应相结合,可能提供预防或延迟发病率和死亡率的潜力。在这篇综述中,我们讨论了可用于检测亚临床动脉粥样硬化性心血管疾病(颈动脉超声、冠状动脉钙化)和非动脉粥样硬化性心血管疾病(超声心动图)的成像技术。我们回顾了这些成像方式,包括原理、相关性、可行性、利用和在LMICs中的使用。如果更早的检测导致更早地参与到医疗保健系统中来预防或延迟心脏事件、发病率和过早死亡,那么在检测亚临床心血管疾病方面的潜在收益可能在LMICs中是巨大的。因此,有必要开展专门的研究来检验检测LMICs亚临床心血管疾病的可行性、实用性和成本效益。
Cardiovascular disease (CVD) is the leading cause of mortality worldwide and also exerts a significant economic burden, especially in low- and middle-income countries (LMICs). Detection of subclinical CVD, before an individual experiences a major event, may therefore offer the potential to prevent or delay morbidity and mortality, if combined with an appropriate care response. In this review, we discuss imaging technologies that can be used to detect subclinical atherosclerotic CVD (carotid ultrasound, coronary artery calcification) and non-atherosclerotic CVD (echocardiography). We review these imaging modalities, including aspects such as rationale, relevance, feasibility, utilization, and access in LMICs. The potential gains in detecting subclinical CVD may be substantial in LMICs, if earlier detection leads to earlier engagement with the health care system to prevent or delay cardiac events, morbidity, and premature mortality. Thus, dedicated studies examining the feasibility, utility, and cost-effectiveness of detecting subclinical CVD in LMICs are warranted.
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