Deciphering Potential Correlations between New Biomarkers and Pattern Classification in Chinese Medicine by Bioinformatics: Two Examples of Rheumatoid Arthritis
Deciphering Potential Correlations between New Biomarkers and Pattern Classification in Chinese Medicine by Bioinformatics: Two Examples of Rheumatoid Arthritis
复制标题
用生物信息学解读新生物标志物与中医证候分类之间的潜在相关性:类风湿关节炎的两个例子
DOI:
10.1007/s11655-018-2571-8
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发表时间:
2018-10
影响因子:
2.9
通讯作者:
Ai ping Lu
中科院分区:
文献类型:
--
作者:
Chi Zhang;Li Li;Ge Zhang;Ke ji Chen;Ai ping Lu
Biological complexity and the need for personalized medicine means that biomarker development has become increasingly challenging. Thus, new paradigms for research need to be created that bring together a different classifier of individuals. One potential solution is collaboration between biomarker development and Chinese medicine pattern classification. In this article, two examples of rheumatoid arthritis are discussed, including a new biomarker candidate casein kinase 2 interacting protein 1 (CKIP-1) and a micro RNA 214. The authors obtained a “snapshot” of pattern classification with disease in biomarker identification. Bioinformatics analyses revealed underlying biological functions of two biomarker candidates, in varying degrees, are correlated with Chinese medicine pattern of rheumatoid arthritis. The authors’ initial attempt can provide a new window for studying the win-win potential correlation between the biomarkers and pattern classification in Chinese medicine.
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DOI:
10.1155/2012/203043
发表时间:
2012
期刊:
Evidence-based complementary and alternative medicine : eCAM
影响因子:
--
作者:
Lu C;Niu X;Xiao C;Chen G;Zha Q;Guo H;Jiang M;Lu A
通讯作者:
Lu A
影响因子:
16.6
作者:
Li D;Liu J;Guo B;Liang C;Dang L;Lu C;He X;Cheung HY;Xu L;Lu C;He B;Liu B;Shaikh AB;Li F;Wang L;Yang Z;Au DW;Peng S;Zhang Z;Zhang BT;Pan X;Qian A;Shang P;Xiao L;Jiang B;Wong CK;Xu J;Bian Z;Liang Z;Guo DA;Zhu H;Tan W;Lu A;Zhang G
通讯作者:
Zhang G
DOI:
--
发表时间:
2006
期刊:
--
影响因子:
--
作者:
L. Ai-ping
通讯作者:
L. Ai-ping
影响因子:
4.6
作者:
Jiang M;Zha Q;Zhang C;Lu C;Yan X;Zhu W;Liu W;Tu S;Hou L;Wang C;Zhang W;Liang Q;Fan B;Yu J;Zhang W;Liu X;Yang J;He X;Li L;Niu X;Liu Y;Guo H;He B;Zhang G;Bian Z;Lu A
通讯作者:
Lu A
影响因子:
4.1
作者:
Guo, Baosheng;Zhang, Baoting;Zhang, Ge
通讯作者:
Zhang, Ge