Relationship of changes in strain rate indices estimated from velocity-encoded MR imaging to loss of muscle force following disuse atrophy.
Relationship of changes in strain rate indices estimated from velocity-encoded MR imaging to loss of muscle force following disuse atrophy.
复制标题
DOI：
10.1002/mrm.26759
复制
发表时间：
2018-03
影响因子：
3.3
通讯作者：
Sinha S
中科院分区：
文献类型：
--
作者：
Malis V;Sinha U;Csapo R;Narici M;Sinha S
This study explores changes in strain rate (rate of regional deformation) parameters extracted from velocity encoded MRI and their relationship to muscle force loss following 4-week unilateral lower limb suspension (ULLS) in healthy humans. 2D SR maps were derived from three directional velocity encoded magnetic resonance phase-contrast images of the medial gastrocnemius in seven subjects. Atrophy related and regional differences in the SR eigenvalues, angle between the SR and muscle fiber (SR-fiber angle), and strain rates in the fiber basis were statistically analyzed using ANOVA and linear regression. During isometric contraction, SR in the fiber cross-section (SRin-plane) was significantly lower and SR-fiber angle was significantly higher post- suspension (P<0.05). On multiple variable regression analysis, volume of medial gastrocnemius, SRin-plane, and SR-fiber angle were significantly associated with force and changes in the, SR eigenvalues and shear strain rate were significantly associated with change in force with disuse. Changes in SR-fiber angle, SRin-plane and shear strain rate as well as their ability to predict force/force changes may reflect the role of remodeling of the extracellular matrix in disuse atrophy and its functional consequence in reducing lateral transmission of force.
登录
查看更多内容
影响因子：
11.2
作者：
GLASS, GV;PECKHAM, PD;SANDERS, JR
通讯作者：
SANDERS, JR
影响因子：
--
作者：
Kim H;Yoo L;Shin A;Demer JL
通讯作者：
Demer JL
DOI：
10.1016/j.biocel.2013.06.011
发表时间：
2013-10
影响因子：
4
作者：
Bodine, Sue C.
通讯作者：
Bodine, Sue C.
影响因子：
5.5
作者：
D'Antona, G;Pellegrino, MA;Bottinelli, R
通讯作者：
Bottinelli, R
DOI：
10.1152/ajpendo.00472.2014
发表时间：
2015-01-15
影响因子：
5.1
作者：
Bongers, Kale S.;Fox, Daniel K.;Adams, Christopher M.
通讯作者：
Adams, Christopher M.