The application of hepatic P450 reductase null gpt delta mice in studying the role of hepatic P450 in genotoxic carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced mutagenesis

The application of hepatic P450 reductase null gpt delta mice in studying the role of hepatic P450 in genotoxic carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced mutagenesis
复制标题

肝P450还原酶缺失gpt delta小鼠在研究肝P450在遗传毒性致癌物4-(甲基亚硝基氨基)-1-(3-吡啶基)-1-丁酮诱变中的作用

DOI:
10.1007/s00204-012-0891-6
复制
发表时间:
2012-06
影响因子:
6.1
通讯作者:
Gu Jun
Gu Jun
中科院分区:
医学2区
文献类型:
--
作者:
Ren Jin;Xing Guozhen;Qi Xinming;Wu Mengjun;Li Chenggang;Yao Jun;Gong Likun;Nohmi Takehiko;Gu Jun

文献摘要

参考文献

相似文献

细胞色素P450(P450或CYP1A1)参与许多致癌物的解毒和代谢活化。为了确定肝P450在遗传毒性致癌物致突变中的作用,我们构建了一种新的肝P450还原酶空载体,
The cytochrome P450 (P450 or CYP) is involved in both detoxification and metabolic activation of many carcinogens. In order to identify the role of hepatic P450 in the mutagenesis of genotoxic carcinogens, we generated a novel hepatic P450 reductase null
DOI: 10.1016/s0027-5107(00)00002-6
发表时间: 2000-03
期刊: Mutation research
影响因子: --
作者:
B. S. Shane;D.L Smith-Dunn;J. G. deBoer;B. W. Glickman;M.L Cunningham
通讯作者: B. S. Shane;D.L Smith-Dunn;J. G. deBoer;B. W. Glickman;M.L Cunningham
DOI: 10.1073/pnas.63.2.428
发表时间: 1969-01-01
影响因子: 11.1
作者:
CLEAVER, JE
通讯作者: CLEAVER, JE
DOI: 10.1002/(sici)1098-2280(1996)28:4
发表时间: 1996
影响因子: 2.8
作者:
N. Gorelick;J. Mirsalis
通讯作者: N. Gorelick;J. Mirsalis
DOI: --
发表时间: 1996-08
期刊: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
影响因子: --
作者:
S. Hecht;N. Trushin;J. Rigotty;S. Carmella;A. Borukhova;S. Akerkar;A. Rivenson
通讯作者: S. Hecht;N. Trushin;J. Rigotty;S. Carmella;A. Borukhova;S. Akerkar;A. Rivenson
DOI: 10.1093/carcin/10.1.1
发表时间: 1989
期刊: Carcinogenesis
影响因子: 4.7
作者:
W. Kaufmann
通讯作者: W. Kaufmann