Design and rationale for NOURISH-T: a randomized control trial targeting parents of overweight children off cancer treatment.
Design and rationale for NOURISH-T: a randomized control trial targeting parents of overweight children off cancer treatment.
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DOI：
10.1016/j.cct.2014.12.018
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发表时间：
2015-03
影响因子：
2.2
通讯作者：
Mazzeo S
中科院分区：
文献类型：
--
作者：
Stern M;Ewing L;Davila E;Thompson AL;Hale G;Mazzeo S
大约 40% 停止治疗的儿科癌症幸存者 (PCS) 超重或肥胖，这增加了他们出现长期身体健康不良并发症的风险。与医学研究所 (IOM) 强调患者从治疗过渡到癌症生存以及增加这些幸存者的长期健康行为的强调一致，我们开展了一项试点随机对照试验，通过将 PCS 的护理人员作为 PCS 行为改变的推动者，解决 PCS 中不断增加的超重/肥胖率。我们重点关注父母在促进 PCS 患者健康饮食和身体活动 (PA) 方面的行为、态度和角色，并采用循证、手动的父母干预措施——NOURISH，该干预措施被发现对超重和肥胖儿童和青少年的父母有效。我们为 5 – 12 岁 PCS 的护理人员（距离积极癌症治疗 6 个月至 4 年）采用 NOURISH。我们的试点可行性 RCT-NOURISH-T（滋养我们对角色建模的理解，以改善对健康转变的支持）评估：1）与增强型日常护理 (EUC) 控制条件相比，NOURISH-T 对 PCS 的初步有效性，以及 2) 改善干预措施未来适应性的考虑因素，包括确定提供干预措施的最佳癌症后治疗时间。该项目将让两个儿科肿瘤诊所的 PCS 护理人员参加为期 6 周的干预（或 EUC），并在 6 周干预前后以及 4 个月的随访中进行评估。
Approximately 40% of off-treatment pediatric cancer survivors (PCS) are overweight or obese, which increases their risk for negative long-term physical health complications. Consistent with the Institute of Medicine’s (IOM) emphasis on patients transitioning from treatment to cancer survivorship and increasing long-term healthy behaviors in these survivors, we conduct a pilot RCT to address the increasing overweight/obesity rates among PCS by targeting their caregivers as agents for PCS behavior change. We focus on parents’ behaviors, attitudes and roles in promoting healthier eating and physical activity (PA) in PCS and adapt an evidence-informed, manualized parent intervention -- NOURISH -- found to be effective for parents of overweight and obese children and adolescents. We adapt NOURISH for caregivers of 5 – 12 year old PCS (6 months-4 years off active cancer treatment). Our pilot feasibility RCT– NOURISH-T (Nourishing Our Understanding of Role modeling to Improve Support for Healthy Transitions) evaluates: 1) the preliminary effectiveness of NOURISH-T for PCS, compared with an Enhanced Usual Care (EUC) control condition, and 2) factors to consider to improve future adaptations of the intervention, including determining optimum post-cancer treatment time to offer the intervention. The project will enroll caregivers of PCS at two pediatric oncology clinics into the 6-week intervention (or EUC) with assessments occurring pre- and post- 6 weeks of intervention, and at a 4-month follow-up.
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影响因子：
3.6
作者：
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通讯作者：
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