Molecular evidence of clonal Vibrio parahaemolyticus pandemic strains.
Molecular evidence of clonal Vibrio parahaemolyticus pandemic strains.
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DOI：
10.3201/eid0606.000612
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发表时间：
2000-11
影响因子：
11.8
通讯作者：
Nair GB
中科院分区：
文献类型：
--
作者：
Chowdhury NR;Chakraborty S;Ramamurthy T;Nishibuchi M;Yamasaki S;Takeda Y;Nair GB
在过去5年中，副溶血性弧菌感染的全球发病率激增归因于最近出现的三种具有大流行潜力的血清型：O3：K6、O4：K68和O1：K无法分型（KUT）。这些血清型的35株，从不同国家分离超过4年，其特征在于核糖分型和脉冲场凝胶电泳，以确定其来源。这些血清型菌株的核糖体型是不可区分的，除了日本tdh阴性O3：K6菌株和美国临床O3：K6分离株，其具有略微不同的谱。菌株总DNA NotI消化的迁移模式相似，血清型之间仅观察到轻微变化。相比之下，1995年以前分离的O3：K6和O1：KUT菌株与其他血清型菌株具有明显不同的特征。O4：K68和O1：KUT毒株最有可能来源于大流行O3：K6克隆。
The upsurge in worldwide incidence of Vibrio parahaemolyticus infection in the last 5 years has been attributed to the recent appearance of three serotypes with pandemic potential: O3:K6, O4:K68, and O1:K untypeable (KUT). Thirty-five strains of these serotypes, isolated from different countries over 4 years, were characterized by ribotyping and pulsed-field gel electrophoresis to determine their origin. The ribotypes of the strains of these serotypes were indistinguishable, except for a Japanese tdh- negative O3:K6 strain and a U.S. clinical O3:K6 isolate, which had slightly different profiles. The migration patterns of the NotI-digest of the total DNA of the strains were similar, and only slight variations were observed between the serotypes. By contrast, the O3:K6 and O1:KUT strains isolated before 1995 and strains of other serotypes had markedly different profiles. The O4:K68 and O1:KUT strains most likely originated from the pandemic O3:K6 clone.
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影响因子：
3.1
作者：
SHIRAI, H;ITO, H;NISHIBUCHI, M
通讯作者：
NISHIBUCHI, M
影响因子：
14.9
作者：
MURRAY, MG;THOMPSON, WF
通讯作者：
THOMPSON, WF
影响因子：
9.4
作者：
Okuda, N;Ishibashi, M;Nishibuchi, M
通讯作者：
Nishibuchi, M
影响因子：
3.1
作者：
HONDA, T;NI, YX;MIWATANI, T
通讯作者：
MIWATANI, T
影响因子：
3.1
作者：
SAKURAI, J;MATSUZAKI, A;MIWATANI, T
通讯作者：
MIWATANI, T