Comparative Transcriptome Analysis Providing Resistance Mechanism of Aspergillus oryzae Under Arsenate Stress
Comparative Transcriptome Analysis Providing Resistance Mechanism of Aspergillus oryzae Under Arsenate Stress
复制标题
比较转录组分析提供米曲霉在砷酸盐胁迫下的抗性机制
DOI：
10.1080/01490451.2021.1877854
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发表时间：
2021-01
影响因子：
2.3
通讯作者：
Wencheng Song
中科院分区：
文献类型：
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作者：
Jun Liang;Lei Liu;Tingqing Cheng;Wencheng Song
摘要 通过比较转录组分析研究了米曲霉（A. oryzae）在砷酸盐（As(V)）胁迫下的分子抗性机制。在As(V)作用下，共检测到4911个米曲霉的差异表达基因（DEGs）
Abstract The molecular resistance mechanism of Aspergillus oryzae (A. oryzae) under arsenate (As(V)) stress was investigated by comparative transcriptome analysis. In total, 4911 differentially expressed genes (DEGs) of A. oryzae were detected under As(V) stress, including 2103 up-regulated genes and 2808 down-regulated genes. Genes induced by As(V) were involved in metal ion binding and transportation, redox homeostasis, efflux carrier, DNA repair, volatilization, etc. Moreover, eight genes were selected for qRT-PCR verification, and their trends were consistent with RNA-Seq analysis, which proved that RNA-Seq analysis was efficient and reliable. The results indicated that the extracellular and intracellular synergistic resistance mechanisms contributed to the improvement of A. oryzae resistance to As (V).
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DOI：
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发表时间：
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期刊：
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影响因子：
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作者：
Bibin Paulose;S. Kandasamy;Om Parkash Dhankher
通讯作者：
Bibin Paulose;S. Kandasamy;Om Parkash Dhankher
影响因子：
7.4
作者：
Cobbett, CS
通讯作者：
Cobbett, CS
影响因子：
46.9
作者：
Trapnell C;Williams BA;Pertea G;Mortazavi A;Kwan G;van Baren MJ;Salzberg SL;Wold BJ;Pachter L
通讯作者：
Pachter L
影响因子：
3.8
作者：
Qu, Wei;Waalkes, Michael P.
通讯作者：
Waalkes, Michael P.
影响因子：
27.5
作者：
Liu, Fang;Chang, Xiao-Jian;Lian, Xing-Ming
通讯作者：
Lian, Xing-Ming