Change in stress and social support as predictors of cognitive decline in older adults with and without depression.
Change in stress and social support as predictors of cognitive decline in older adults with and without depression.
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DOI：
10.1002/gps.2676
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发表时间：
2011-12
影响因子：
4
通讯作者：
Steffens, David C.
中科院分区：
文献类型：
--
作者：
Dickinson, Whitney J.;Potter, Guy G.;Hybels, Celia F.;McQuoid, Douglas R.;Steffens, David C.
压力、社会支持与认知在老年抑郁症中的关系是复杂的。在这项研究中，我们试图检查压力生活事件的增加或社会支持的减少是否会导致患有和不患有抑郁症的老年人随后的认知能力下降。样本包括112名抑郁症老年人和101名非抑郁症老年人，他们参加了老年人抑郁症的神经认知结果（NCODE）研究。参与者接受临床评估，同意接受以压力生活事件和社会支持为重点的访谈，并每年接受一系列神经心理学测试。我们的全球认知测量是建立阿尔茨海默病总评分注册联盟（CERAD TS）。我们发现，压力源总数的减少与随后CERAD TS的改善有关。在社会支持方面，社会互动和工具性社会支持的减少预示着认知表现的下降。即使在控制了抑郁状态、年龄、教育程度和性别之后，这些关系也很显著。这些发现扩展了之前关于社会因素在衰老和抑郁中的重要性的研究，这些研究主要集中在情绪相关的结果上。需要进一步的确证性研究。此外，还需要进行生物学和其他方面的研究，以进一步了解压力、社会支持和认知在患有和不患有抑郁症的老年人中的关系。
The relationship between stress, social support and cognition in geriatric depression is complex. In this study, we sought to examine whether an increase in stressful life events or a decrease in social support would lead to subsequent cognitive decline among older adults with and without depression. The sample consisted of 112 depressed and 101 non-depressed older adults who enrolled in the Neurocognitive Outcomes of Depression in the Elderly (NCODE) study. Participants were assessed clinically, agreed to interviews focusing on stressful life events and social support, and underwent a battery of neuropsychological tests annually. Our global measure of cognition was the Consortium to Establish a Registry in Alzheimer’s disease Total Score (CERAD TS). We found that a decline in the total number of stressors was associated with a subsequent improvement on CERAD TS. In terms of social support, decreased social interaction and instrumental social support predicted decline in cognitive performance. These relationships were significant even after controlling for depression status, age, education, and sex. These findings extend prior research on the importance of social factors in aging and depression which have largely focused on mood-related outcomes. Future confirmatory studies are needed. In addition, biological and other studies should be conducted to further our understanding of the relationship between stress, social support and cognition in older adults with and without depression.
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影响因子：
3.9
作者：
Hoppe, C;M端ller, U;von Cramon, DY
通讯作者：
von Cramon, DY
影响因子：
39.2
作者：
Bassuk, SS;Glass, TA;Berkman, LF
通讯作者：
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影响因子：
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作者：
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通讯作者：
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影响因子：
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作者：
LANDERMAN, R;GEORGE, LK;BLAZER, DG
通讯作者：
BLAZER, DG
DOI：
10.1093/geronb/59.6.p278
发表时间：
2004-11-01
影响因子：
6.2
作者：
Holtzman, RE;Rebok, GW;Eaton, WW
通讯作者：
Eaton, WW