Innate Immunity to Staphylococcus aureus: Evolving Paradigms in Soft Tissue and Invasive Infections.
Innate Immunity to Staphylococcus aureus: Evolving Paradigms in Soft Tissue and Invasive Infections.
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DOI：
10.4049/jimmunol.1701574
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发表时间：
2018-06-15
期刊：
影响因子：
--
通讯作者：
Serezani CH
中科院分区：
文献类型：
--
作者：
Brandt SL;Putnam NE;Cassat JE;Serezani CH
金黄色葡萄球菌引起广泛的疾病，这些疾病共同构成了重大的公共卫生负担。在代谢灵活性和大毒力库的帮助下，S。金黄色葡萄球菌具有显著的造血传播和感染各种组织的能力，所述组织包括皮肤、肺、心脏和骨等。侵袭性葡萄球菌感染的标志性病变，即脓肿，同时表示对组织侵袭的强大先天免疫应答，以及葡萄球菌在这些病变内持续存在的能力。本文综述了S.金黄色葡萄球菌在皮肤和骨骼感染期间，分别作为软组织和骨骼疾病的范例。
Staphylococcus aureus causes a wide range of diseases that together embody a significant public health burden. Aided by metabolic flexibility and a large virulence repertoire, S. aureus has the remarkable ability to hematogenously disseminate and infect various tissues, including skin, lung, heart, and bone, among others. The hallmark lesions of invasive staphylococcal infections, abscesses, simultaneously denote the powerful innate immune responses to tissue invasion, as well as the ability of staphylococci to persist within these lesions. In this manuscript, we review the innate immune responses to S. aureus during infection of skin and bone, which serve as paradigms for soft tissue and bone disease, respectively.
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影响因子：
2.8
作者：
Bernthal, Nicholas M.;Pribaz, Jonathan R.;Stavrakis, Alexandra I.;Billi, Fabrizio;Cho, John S.;Ramos, Romela Irene;Francis, Kevin P.;Iwakura, Yoichiro;Miller, Lloyd S.
通讯作者：
Miller, Lloyd S.
影响因子：
8
作者：
Bocchini, CE;Hulten, KG;Kaplan, SL
通讯作者：
Kaplan, SL
DOI：
10.1002/jbmr.3055
发表时间：
2017-05
期刊：
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
影响因子：
--
作者：
de Mesy Bentley KL;Trombetta R;Nishitani K;Bello-Irizarry SN;Ninomiya M;Zhang L;Chung HL;McGrath JL;Daiss JL;Awad HA;Kates SL;Schwarz EM
通讯作者：
Schwarz EM
影响因子：
5.3
作者：
Ahn D;Prince A
通讯作者：
Prince A
DOI：
10.1111/j.1469-0691.2008.02648.x
发表时间：
2009-02
期刊：
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
影响因子：
--
作者：
Brown EL;Dumitrescu O;Thomas D;Badiou C;Koers EM;Choudhury P;Vazquez V;Etienne J;Lina G;Vandenesch F;Bowden MG
通讯作者：
Bowden MG