Recent Advances in Astragalus membranaceus Anti-Diabetic Research: Pharmacological Effects of Its Phytochemical Constituents.
Recent Advances in Astragalus membranaceus Anti-Diabetic Research: Pharmacological Effects of Its Phytochemical Constituents.
复制标题
黄芪抗糖尿病研究新进展：其植物化学成分的药理作用
DOI：
10.1155/2013/654643
复制
发表时间：
2013
期刊：
影响因子：
--
通讯作者：
Gao X
中科院分区：
文献类型：
--
作者：
Agyemang K;Han L;Liu E;Zhang Y;Wang T;Gao X
糖尿病的疾病负担在全世界范围内都在增加。需要更有效的药物来补充目前的抗糖尿病药物已成为当务之急。黄芪是大多数中草药抗糖尿病配方中的关键成分，是开发含铅抗糖尿病化合物的重要开发方向。它的抗糖尿病特性已被逐步研究。民族药理学研究已经确定了其缓解糖尿病的潜力。最近的研究试图将其化学成分与1型和2型糖尿病联系起来。对其总多糖、皂苷、黄酮级分和几个分离出的化合物的研究最多。总多糖组分对1型糖尿病和2型糖尿病均有一定的抑制作用。本文讨论了与1型和2型糖尿病相关的化学成分的抗糖尿病作用和药理作用。
The disease burden of diabetes mellitus is increasing throughout the world. The need for more potent drugs to complement the present anti-diabetic drugs has become an imperative. Astragalus membranaceus, a key component of most Chinese herbal anti-diabetic formulas, has been an important prospect for lead anti-diabetic compounds. It has been progressively studied for its anti-diabetic properties. Ethnopharmacological studies have established its potential to alleviate diabetes mellitus. Recent studies have sought to relate its chemical constituents to types 1 and 2 diabetes mellitus. Its total polysaccharides, saponins, and flavonoids fractions and several isolated compounds have been the most studied. The total polysaccharides fraction demonstrated activity to both types 1 and 2 diabetes mellitus. This paper discusses the anti-diabetic effects and pharmacological action of the chemical constituents in relation to types 1 and 2 diabetes mellitus.
登录
查看更多内容
影响因子：
7.7
作者：
Karlsson, HKR;Zierath, JR;Wallberg-Henriksson, H
通讯作者：
Wallberg-Henriksson, H
影响因子：
1.7
作者：
Kim, Ju Sun;Yean, Min-Hye;Kang, Sam Sik
通讯作者：
Kang, Sam Sik
影响因子：
1.8
作者：
Chen, W.;Li, Y. -M.;Yu, M. -H.
通讯作者：
Yu, M. -H.
影响因子：
2.4
作者：
Guri AJ;Mohapatra SK;Horne WT 2nd;Hontecillas R;Bassaganya-Riera J
通讯作者：
Bassaganya-Riera J
DOI：
10.1128/cdli.6.3.306-310.1999
发表时间：
1999-05-01
期刊：
CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY
影响因子：
--
作者：
Azar, ST;Tamim, H;Almawi, WY
通讯作者：
Almawi, WY