Thrombin-induced platelet calcium mobilization is enhanced in bipolar disorders

Thrombin-induced platelet calcium mobilization is enhanced in bipolar disorders
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双相情感障碍中凝血酶诱导的血小板钙动员增强

DOI:
10.1016/0006-3223(92)90305-j
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发表时间:
1992
影响因子:
10.6
通讯作者:
I. Yamashita
I. Yamashita
中科院分区:
医学1区
文献类型:
--
作者:
I. Kusumi;T. Koyama;I. Yamashita

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对53例抑郁症患者(14例双相情感障碍,23例伴抑郁症,16例不伴抑郁症),5例强迫症患者,4例精神分裂症患者和25例健康对照者进行凝血酶诱导的细胞内钙动员(TICM)检测。受试者完成了汉密尔顿抑郁评定量表。结果表明,双相抑郁症患者的TICM反应高于伴或不伴抑郁症的抑郁症患者,也高于对照组。患者组与对照组基础Ca2+浓度无显著性差异。未发现TICM反应与症状严重程度之间的关系。(PsycINFO数据库记录(c)2018阿帕,保留所有权利)
Assessed thrombin-induced intracellular Ca mobilization (TICM) in 53 depressed Ss (14 with bipolar disorder, 23 with major depression with melancholia, and 16 with major depression without melancholia), 5 Ss with obsessive-compulsive disorder, 4 schizophrenics, and 25 healthy controls. Ss completed the Hamilton Rating Scale for Depression. Results show that the TICM response in bipolar depression was higher than in major depression with or without melancholia and higher than that in controls. No significant difference was found in basal Ca 2+ concentration between patient groups and controls. No relationship was found between TICM response and severity of symptoms.(PsycINFO Database Record (c) 2018 APA, all rights reserved)
锂对双相情感障碍(躁狂抑郁症)患者和健康对照者血小板离子胞内钙浓度的影响。
DOI: 10.1016/0024-3205(90)90454-y
发表时间: 1990
期刊: Life sciences
影响因子: 6.1
作者:
Tan,CH;Javors,MA;Seleshi,E;Lowrimore,PA;Bowden,CL
通讯作者: Bowden,CL