Human masseter muscle fiber type properties, skeletal malocclusions, and muscle growth factor expression.
Human masseter muscle fiber type properties, skeletal malocclusions, and muscle growth factor expression.
复制标题
DOI：
10.1016/j.joms.2011.04.007
复制
发表时间：
2012-02
期刊：
影响因子：
--
通讯作者：
Raoul G
中科院分区：
文献类型：
--
作者：
Sciote JJ;Horton MJ;Rowlerson AM;Ferri J;Close JM;Raoul G
我们确定了牙面部畸形受试者的咬肌纤维类型属性差异。在下颌截骨术过程中从 139 名年轻人身上采集了咬肌样本，以评估构成肌肉的 4 种纤维类型的平均纤维面积和组织占有率。根据是否存在骨性 II 类或 III 类矢状尺寸错牙合以及骨骼性开放型、深型或正常咬合垂直尺寸错牙合，将受试者分为 6 个错牙合组中的一组。在亚群中，通过实时聚合酶链式反应对肌肉生长因子 IGF-I 和 GDF-8 基因表达的相对量进行定量。矢状错牙合组的纤维特性没有差异，但垂直错牙合组的纤维特性差异很大 (P ≤ .0004)。 II 型 (P ≤ .0004) 和新生儿心房型 (P = .001) 纤维类型的平均纤维面积存在显着差异，I-II 型混合纤维和 II 型纤维 (P ≤ .0004) 的纤维占用百分比差异也存在显着差异。 IGF-I (P = .02) 和 GDF-8 (P < .01) 的生长因子表达因性别而异。 IGF-I:GDF-8 表达比率与 I 型和 II 型平均纤维面积相关。纤维类型特性与面部垂直生长的变化密切相关，总体比较具有统计显着性（P ≤ .0004）。 II 型咬肌纤维平均纤维面积和组织占有率的增加与垂直面部尺寸的增加呈负相关。
We identified masseter muscle fiber type property differences in subjects with dentofacial deformities. Samples of masseter muscle were collected from 139 young adults during mandibular osteotomy procedures to assess mean fiber areas and percent tissue occupancies for the 4 fiber types that comprise the muscle. Subjects were classified into 1 of 6 malocclusion groups based on the presence of a skeletal Class II or III sagittal dimension malocclusion and either a skeletal open, deep, or normal bite vertical dimension malocclusion. In a subpopulation, relative quantities of the muscle growth factors IGF-I and GDF-8 gene expression were quantified by real-time polymerase chain reaction. Fiber properties were not different in the sagittal malocclusion groups, but were very different in the vertical malocclusion groups (P ≤ .0004). There were significant mean fiber area differences for type II (P ≤ .0004) and type neonatal—atrial (P = .001) fiber types and for fiber percent occupancy differences for both type I–II hybrid fibers and type II fibers (P ≤ .0004). Growth factor expression differed by gender for IGF-I (P = .02) and GDF-8 (P < .01). The ratio of IGF-I:GDF-8 expression associates with type I and II mean fiber areas. Fiber type properties are very closely associated with variations in vertical growth of the face, with statistical significance for overall comparisons at P ≤ .0004. An increase in masseter muscle type II fiber mean fiber areas and percent tissue occupancies is inversely related to increases in vertical facial dimension.
登录
查看更多内容
影响因子：
3
作者：
Boom, H. P. W.;van Spronsena, P. H.;Tuinzing, D. B.
通讯作者：
Tuinzing, D. B.
DOI：
10.1016/s0002-9416(84)90035-6
发表时间：
1984-01-01
影响因子：
3
作者：
CORRUCCINI, RS
通讯作者：
CORRUCCINI, RS
影响因子：
56.9
作者：
CORRUCCINI, RS;BEECHER, RM
通讯作者：
BEECHER, RM
影响因子：
3.1
作者：
Gedrange, Tomas;Buettner, Cordula;Harzer, Winfried
通讯作者：
Harzer, Winfried
DOI：
10.1111/j.1748-1716.1988.tb08501.x
发表时间：
1988-11-01
期刊：
ACTA PHYSIOLOGICA SCANDINAVICA
影响因子：
--
作者：
GERDLE, B;WRETLING, ML;HENRIKSSONLARSEN, K
通讯作者：
HENRIKSSONLARSEN, K