Mitophagy mechanisms and role in human diseases.
Mitophagy mechanisms and role in human diseases.
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DOI:
10.1016/j.biocel.2014.05.010
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发表时间:
2014-08
影响因子:
4
通讯作者:
Zhang, Jianhua
中科院分区:
文献类型:
--
作者:
Redmann, Matthew;Dodson, Matthew;Boyer-Guittaut, Michael;Darley-Usmar, Victor;Zhang, Jianhua
Mitophagy is a process of mitochondrial turnover through lysosomal mediated autophagy activities. This review will highlight recent studies that have identified mediators of mitophagy in response to starvation, loss of mitochondrial membrane potential or perturbation of mitochondrial integrity. Furthermore, we will review evidence of mitophagy dysfunction in various human diseases and discuss the potential for therapeutic interventions that target mitophagy processes.
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影响因子:
3.4
作者:
Dorn GW 2nd
通讯作者:
Dorn GW 2nd
影响因子:
7.4
作者:
Dodson, Matthew;Darley-Usmar, Victor;Zhang, Jianhua
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3.5
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Gegg, Matthew E.;Cooper, J. Mark;Taanman, Jan-Willem
通讯作者:
Taanman, Jan-Willem