The Framingham Heart Study's impact on global risk assessment.
The Framingham Heart Study's impact on global risk assessment.
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DOI：
10.1016/j.pcad.2010.04.001
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发表时间：
2010-07
影响因子：
9.1
通讯作者：
Gaziano, Thomas
中科院分区：
文献类型：
--
作者：
Bitton, Asaf;Gaziano, Thomas
心血管疾病（CVD）是导致死亡的主要原因，占全球死亡人数的约30%。在全球范围内，80%的CVD死亡发生在发展中国家。近年来，在发达国家，年龄调整的心血管疾病死亡率已减少一半。大部分的下降是由于风险因素的减少，这是心脏病研究帮助确定的。心脏病研究还通过创建多变量风险评分来帮助对那些风险最高的人进行分类。因此，其他研究人员为他们的国家创建了各种风险预测分数。这些评分一直是发达国家指导方针和预防战略的基础。然而，大多数需要验血的评分可能难以在筛查资源有限的发展中国家实施。受心脏病研究启发的新研究和风险评分需要简化发展中国家的风险评分，以便实施负担得起的预防策略。
Cardiovascular Disease (CVD) is the leading cause of mortality, responsible for about 30 percent of deaths worldwide. Globally, 80 percent of total CVD deaths occur in developing countries. In recent years age-adjusted CVD death has been cut in half in developed countries. Much of the decline is due to reductions in risk factors which the Framingham Heart Study helped to identify. The Framingham Heart Study also helped to classify those at highest risk by creating multivariate risk scores. As a result other investigators have created various risk prediction scores for their countries. These scores have been the foundation for guidelines and prevention strategies in developed countries. However, most scores requiring blood tests may be difficult to implement in developing countries where limited resources for screening exist. New studies and risk scores inspired by the Framingham Heart Study need to simplify risk scoring in developing countries so affordable prevention strategies can be implemented.
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