Bioinformatics-Based Activities in High School: Fostering Students' Literacy, Interest, and Attitudes on Gene Regulation, Genomics, and Evolution.

Bioinformatics-Based Activities in High School: Fostering Students' Literacy, Interest, and Attitudes on Gene Regulation, Genomics, and Evolution.
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DOI:
10.3389/fmicb.2020.578099
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发表时间:
2020
影响因子:
5.2
通讯作者:
Tavares F
Tavares F
中科院分区:
生物学2区
文献类型:
--
作者:
Martins A;Fonseca MJ;Lemos M;Lencastre L;Tavares F

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生物信息学在解释生物现象中的关键作用要求需要重新思考高中的教学方法,使其与新的科学现实相一致。尽管采取了一些在课堂上引入生物信息学的举措,但仍然缺乏对其对学生学习收获、参与度和动机的影响的了解。在这项研究中,我们详细介绍了为高中生物课程量身定制的四个生物信息学实验室,名为“挖掘基因组:在课堂上使用生物信息学工具支持学生发现基因”,对 387 名高中生的读写能力、兴趣和态度产生影响。通过探索这些实验室,学生可以熟悉生物信息学,并认识到许多生物信息学工具对于初学者来说是直观的。此外,在学习实践中引入比较基因组学有助于更好地理解有关基因识别、基因调控以及如何做出进化假设的课程内容。经过干预,学生们能够确定识别基因组序列中的基因所需的生物信息学工具,最重要的是,他们能够解决与基因组学相关的误解。总体而言,学生们对将基于生物信息学的方法整合到学习实践中表现出了积极的态度,增强了他们在教育方法中的附加值。
The key role of bioinformatics in explaining biological phenomena calls for the need to rethink didactic approaches at high school aligned with a new scientific reality. Despite several initiatives to introduce bioinformatics in the classroom, there is still a lack of knowledge on their impact on students’ learning gains, engagement, and motivation. In this study, we detail the effects of four bioinformatics laboratories tailored for high school biology classes named “Mining the Genome: Using Bioinformatics Tools in the Classroom to Support Student Discovery of Genes” on literacy, interest, and attitudes on 387 high school students. By exploring these laboratories, students get acquainted with bioinformatics and acknowledge that many bioinformatics tools can be intuitive for beginners. Furthermore, introducing comparative genomics in their learning practices contributed for a better understanding of curricular contents regarding the identification of genes, their regulation, and how to make evolutionary assumptions. Following the intervention, students were able to pinpoint bioinformatics tools required to identify genes in a genomics sequence, and most importantly, they were able to solve genomics-related misconceptions. Overall, students revealed a positive attitude regarding the integration of bioinformatics-based approaches in their learning practices, reinforcing their added value in educational approaches.
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